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Chimeric antigen receptor T cells persist and induce sustained remissions in relapsed refractory chronic lymphocytic leukemia.
Porter, David L; Hwang, Wei-Ting; Frey, Noelle V; Lacey, Simon F; Shaw, Pamela A; Loren, Alison W; Bagg, Adam; Marcucci, Katherine T; Shen, Angela; Gonzalez, Vanessa; Ambrose, David; Grupp, Stephan A; Chew, Anne; Zheng, Zhaohui; Milone, Michael C; Levine, Bruce L; Melenhorst, Jan J; June, Carl H.
Afiliação
  • Porter DL; Division of Hematology/Oncology, Department of Medicine, and Abramson Cancer Center, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA. david.porter@uphs.upenn.edu cjune@exchange.upenn.edu.
  • Hwang WT; Department of Biostatistics and Epidemiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.
  • Frey NV; Division of Hematology/Oncology, Department of Medicine, and Abramson Cancer Center, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.
  • Lacey SF; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.
  • Shaw PA; Department of Biostatistics and Epidemiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.
  • Loren AW; Division of Hematology/Oncology, Department of Medicine, and Abramson Cancer Center, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.
  • Bagg A; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.
  • Marcucci KT; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.
  • Shen A; Novartis Pharmaceutical Corporation, One Health Plaza, East Hanover, NJ 07936, USA.
  • Gonzalez V; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.
  • Ambrose D; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.
  • Grupp SA; Division of Oncology, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
  • Chew A; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.
  • Zheng Z; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.
  • Milone MC; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.
  • Levine BL; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.
  • Melenhorst JJ; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.
  • June CH; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA. david.porter@uphs.upenn.edu cjune@exchange.upenn.edu.
Sci Transl Med ; 7(303): 303ra139, 2015 Sep 02.
Article em En | MEDLINE | ID: mdl-26333935
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Indução de Remissão / Receptores de Antígenos de Linfócitos T / Linfócitos T / Leucemia Linfocítica Crônica de Células B Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Indução de Remissão / Receptores de Antígenos de Linfócitos T / Linfócitos T / Leucemia Linfocítica Crônica de Células B Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2015 Tipo de documento: Article