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A common polymorphism in the 5' UTR of ERCC5 creates an upstream ORF that confers resistance to platinum-based chemotherapy.
Somers, Joanna; Wilson, Lindsay A; Kilday, John-Paul; Horvilleur, Emilie; Cannell, Ian G; Pöyry, Tuija A A; Cobbold, Laura C; Kondrashov, Alexander; Knight, John R P; Puget, Stéphanie; Grill, Jacques; Grundy, Richard G; Bushell, Martin; Willis, Anne E.
Afiliação
  • Somers J; Medical Research Council Toxicology Unit, Leicester LE1 9HN, United Kingdom;
  • Wilson LA; Medical Research Council Toxicology Unit, Leicester LE1 9HN, United Kingdom;
  • Kilday JP; Children's Brain Tumour Research Centre, The Medical School, University of Nottingham, Nottingham NG7 2UH, United Kingdom;
  • Horvilleur E; Medical Research Council Toxicology Unit, Leicester LE1 9HN, United Kingdom;
  • Cannell IG; Medical Research Council Toxicology Unit, Leicester LE1 9HN, United Kingdom; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA;
  • Pöyry TA; Medical Research Council Toxicology Unit, Leicester LE1 9HN, United Kingdom;
  • Cobbold LC; Medical Research Council Toxicology Unit, Leicester LE1 9HN, United Kingdom;
  • Kondrashov A; School of Pharmacy, University of Nottingham, Nottingham NG7 2RD, United Kingdom;
  • Knight JR; Medical Research Council Toxicology Unit, Leicester LE1 9HN, United Kingdom;
  • Puget S; Departement de Neurochirugie Pédiatrique, Hôpital Necker, University Paris V Descartes, 75006 Paris, France;
  • Grill J; Department of Pediatric and Adolescent Oncology, Institut Gustave Roussy, 94805 Villejuif, France.
  • Grundy RG; Children's Brain Tumour Research Centre, The Medical School, University of Nottingham, Nottingham NG7 2UH, United Kingdom;
  • Bushell M; Medical Research Council Toxicology Unit, Leicester LE1 9HN, United Kingdom;
  • Willis AE; Medical Research Council Toxicology Unit, Leicester LE1 9HN, United Kingdom;
Genes Dev ; 29(18): 1891-6, 2015 Sep 15.
Article em En | MEDLINE | ID: mdl-26338418
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Polimorfismo Genético / Fatores de Transcrição / Proteínas Nucleares / Fases de Leitura Aberta / Resistencia a Medicamentos Antineoplásicos / Regiões 5' não Traduzidas / Proteínas de Ligação a DNA / Endonucleases / Ependimoma Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Polimorfismo Genético / Fatores de Transcrição / Proteínas Nucleares / Fases de Leitura Aberta / Resistencia a Medicamentos Antineoplásicos / Regiões 5' não Traduzidas / Proteínas de Ligação a DNA / Endonucleases / Ependimoma Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article