A cascade of protein aggregation bombards mitochondria for neurodegeneration and apoptosis under WWOX deficiency.

Sze, C I; Kuo, Y M; Hsu, L J; Fu, T F; Chiang, M F; Chang, J Y; Chang, N S

Sze, C I; Kuo, Y M; Hsu, L J; Fu, T F; Chiang, M F; Chang, J Y; Chang, N S.

Afiliação

Sze CI; Department of Cell Biology and Anatomy, National Cheng Kung University, Tainan, Taiwan, ROC.
Kuo YM; Department of Cell Biology and Anatomy, National Cheng Kung University, Tainan, Taiwan, ROC.
Hsu LJ; Department of Medical Laboratory Science and Biotechnology, National Cheng Kung University, Tainan, Taiwan, ROC.
Fu TF; Department of Medical Laboratory Science and Biotechnology, National Cheng Kung University, Tainan, Taiwan, ROC.
Chiang MF; Department of Neurosurgery, MacKay Memorial Hospital Taipei, and Graduate Institute of Injury Prevention and Control, Taipei Medical University, Taipei, Taiwan, ROC.
Chang JY; Institute of Molecular Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan, ROC.
Chang NS; Institute of Molecular Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan, ROC.

Cell Death Dis ; 6: e1881, 2015 Sep 10.

Article em En | MEDLINE | ID: mdl-26355344

Assuntos

Mitocôndrias/metabolismo; Doenças Neurodegenerativas/genética; Doenças Neurodegenerativas/metabolismo; Oxirredutases/genética; Oxirredutases/metabolismo; Proteínas Supressoras de Tumor/genética; Proteínas Supressoras de Tumor/metabolismo; Animais; Apoptose; Humanos; Camundongos; Agregados Proteicos; Oxidorredutase com Domínios WW

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oxirredutases / Doenças Neurodegenerativas / Proteínas Supressoras de Tumor / Mitocôndrias Limite: Animals / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google