The Touching Tail of a Mechanotransduction Channel.

Knecht, Zachary A; Gaudet, Rachelle; Garrity, Paul A

Knecht, Zachary A; Gaudet, Rachelle; Garrity, Paul A.

Afiliação

Knecht ZA; National Center for Behavioral Genomics, Brandeis University, Waltham, MA 02458, USA; Volen Center for Complex Systems, Department of Biology, Brandeis University, Waltham, MA 02458, USA.
Gaudet R; Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA.
Garrity PA; National Center for Behavioral Genomics, Brandeis University, Waltham, MA 02458, USA; Volen Center for Complex Systems, Department of Biology, Brandeis University, Waltham, MA 02458, USA. Electronic address: pgarrity@brandeis.edu.

Cell ; 162(6): 1214-6, 2015 Sep 10.

Article em En | MEDLINE | ID: mdl-26359983

ABSTRACT

ABSTRACT

In mechanotransduction, sensory receptors convert force into electrical signals to mediate such diverse functions as touch, pain, and hearing. In this issue of Cell, Zhang et al. present evidence that the fly NompC channel senses mechanical stimuli using its N-terminal tail as a tether between the cell membrane and microtubules.

Assuntos

Proteínas de Drosophila/química; Proteínas de Drosophila/metabolismo; Drosophila/metabolismo; Mecanotransdução Celular; Canais de Potencial de Receptor Transitório/química; Canais de Potencial de Receptor Transitório/metabolismo; Animais

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas de Drosophila / Mecanotransdução Celular / Drosophila / Canais de Potencial de Receptor Transitório Limite: Animals Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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