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Association of Long Runs of Homozygosity With Alzheimer Disease Among African American Individuals.
Ghani, Mahdi; Reitz, Christiane; Cheng, Rong; Vardarajan, Badri Narayan; Jun, Gyungah; Sato, Christine; Naj, Adam; Rajbhandary, Ruchita; Wang, Li-San; Valladares, Otto; Lin, Chiao-Feng; Larson, Eric B; Graff-Radford, Neill R; Evans, Denis; De Jager, Philip L; Crane, Paul K; Buxbaum, Joseph D; Murrell, Jill R; Raj, Towfique; Ertekin-Taner, Nilufer; Logue, Mark; Baldwin, Clinton T; Green, Robert C; Barnes, Lisa L; Cantwell, Laura B; Fallin, M Daniele; Go, Rodney C P; Griffith, Patrick A; Obisesan, Thomas O; Manly, Jennifer J; Lunetta, Kathryn L; Kamboh, M Ilyas; Lopez, Oscar L; Bennett, David A; Hendrie, Hugh; Hall, Kathleen S; Goate, Alison M; Byrd, Goldie S; Kukull, Walter A; Foroud, Tatiana M; Haines, Jonathan L; Farrer, Lindsay A; Pericak-Vance, Margaret A; Lee, Joseph H; Schellenberg, Gerard D; St George-Hyslop, Peter; Mayeux, Richard; Rogaeva, Ekaterina.
Afiliação
  • Ghani M; Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada.
  • Reitz C; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, New York, New York3Gertrude H. Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, New York4.
  • Cheng R; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, New York, New York.
  • Vardarajan BN; Gertrude H. Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, New York.
  • Jun G; Department of Medicine (Biomedical Genetics), Boston University, Boston, Massachusetts6Department of Biostatistics, Boston University, Boston, Massachusetts7Department of Ophthalmology, Boston University, Boston, Massachusetts.
  • Sato C; Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada.
  • Naj A; The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida.
  • Rajbhandary R; The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida.
  • Wang LS; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia.
  • Valladares O; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia.
  • Lin CF; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia.
  • Larson EB; Department of Medicine, University of Washington, Seattle11Group Health Research Institute, Group Health, Seattle, Washington.
  • Graff-Radford NR; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida13Department of Neurology, Mayo Clinic, Jacksonville, Florida.
  • Evans D; Rush Institute for Healthy Aging, Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois.
  • De Jager PL; Program in Translational Neuropsychiatric Genomics, Department of Neurology, Brigham and Women's Hospital, Boston, Massachusetts16Harvard Medical School, Boston, Massachusetts17Program in Medical and Population Genetics, The Broad Institute, Cambridge, Ma.
  • Crane PK; Department of Medicine, University of Washington, Seattle.
  • Buxbaum JD; Department of Psychiatry, Mount Sinai School of Medicine, New York, New York19Department of Genetics and Genomics Sciences, Mount Sinai School of Medicine, New York, New York20Department of Neuroscience, Mount Sinai School of Medicine, New York, New York2.
  • Murrell JR; Department of Medical and Molecular Genetics, Indiana University, Indianapolis.
  • Raj T; Harvard Medical School, Boston, Massachusetts.
  • Ertekin-Taner N; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida13Department of Neurology, Mayo Clinic, Jacksonville, Florida.
  • Logue M; Department of Medicine (Biomedical Genetics), Boston University, Boston, Massachusetts.
  • Baldwin CT; Department of Medicine (Biomedical Genetics), Boston University, Boston, Massachusetts.
  • Green RC; Harvard Medical School, Boston, Massachusetts23Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts24Partners Center for Personalized Genetic Medicine, Brigham and Women's Hospital, Boston, Massachusetts.
  • Barnes LL; Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois26Department of Behavioral Sciences, Rush University Medical Center, Chicago, Illinois.
  • Cantwell LB; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia.
  • Fallin MD; Department of Epidemiology, Johns Hopkins University School of Public Health, Baltimore, Maryland.
  • Go RC; School of Public Health, University of Alabama at Birmingham.
  • Griffith PA; SABA University School of Medicine, SABA, Dutch Caribbean.
  • Obisesan TO; Division of Geriatrics, Howard University Hospital, Washington, DC.
  • Manly JJ; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, New York, New York4Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, New York.
  • Lunetta KL; Department of Biostatistics, Boston University, Boston, Massachusetts.
  • Kamboh MI; Department of Human Genetics, University of Pittsburgh, Pittsburgh, Pennsylvania32Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh, Pennsylvania.
  • Lopez OL; Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh, Pennsylvania.
  • Bennett DA; Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois33Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois.
  • Hendrie H; Indiana University Center for Aging Research, Indianapolis35Department of Psychiatry, Indiana University School of Medicine, Indianapolis36Regenstrief Institute Inc, Indianapolis, Indiana.
  • Hall KS; Department of Psychiatry, Indiana University School of Medicine, Indianapolis.
  • Goate AM; Hope Center Program on Protein Aggregation and Neurodegeneration, Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri.
  • Byrd GS; Department of Biology, North Carolina A & T University, Greensboro.
  • Kukull WA; National Alzheimer's Coordinating Center, Department of Epidemiology, University of Washington, Seattle.
  • Foroud TM; Department of Behavioral Sciences, Rush University Medical Center, Chicago, Illinois.
  • Haines JL; Vanderbilt Center for Human Genetics Research, Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee.
  • Farrer LA; Department of Medicine (Biomedical Genetics), Boston University, Boston, Massachusetts6Department of Biostatistics, Boston University, Boston, Massachusetts7Department of Ophthalmology, Boston University, Boston, Massachusetts41Department of Neurology, Bo.
  • Pericak-Vance MA; The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida.
  • Lee JH; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, New York, New York3Gertrude H. Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, New York4.
  • Schellenberg GD; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia.
  • St George-Hyslop P; Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada.
  • Mayeux R; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, New York, New York3Gertrude H. Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, New York4.
  • Rogaeva E; Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada.
JAMA Neurol ; 72(11): 1313-23, 2015 Nov.
Article em En | MEDLINE | ID: mdl-26366463
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Negro ou Afro-Americano / Polimorfismo de Nucleotídeo Único / Doença de Alzheimer / Homozigoto Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Aged / Humans País como assunto: America do norte Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Negro ou Afro-Americano / Polimorfismo de Nucleotídeo Único / Doença de Alzheimer / Homozigoto Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Aged / Humans País como assunto: America do norte Idioma: En Ano de publicação: 2015 Tipo de documento: Article