Increased ubiquitination and reduced plasma membrane trafficking of placental amino acid transporter SNAT-2 in human IUGR.

Chen, Yi-Yung; Rosario, Fredrick J; Shehab, Majida Abu; Powell, Theresa L; Gupta, Madhulika B; Jansson, Thomas

Chen, Yi-Yung; Rosario, Fredrick J; Shehab, Majida Abu; Powell, Theresa L; Gupta, Madhulika B; Jansson, Thomas.

Afiliação

Chen YY; Department of Obstetrics & Gynecology, University of Colorado, Anschutz Medical Campus, Aurora, CO 80045, U.S.A. Division of High-risk Pregnancy, Department of Obstetrics & Gynecology, Mackay Memorial Hospital, Taipei 10449, Taiwan yi-yung.chen@ucdenver.edu.
Rosario FJ; Department of Obstetrics & Gynecology, University of Colorado, Anschutz Medical Campus, Aurora, CO 80045, U.S.A.
Shehab MA; Children's Health Research Institute, University of Western Ontario, London, Ontario N6C 2V5, Canada.
Powell TL; Department of Obstetrics & Gynecology, University of Colorado, Anschutz Medical Campus, Aurora, CO 80045, U.S.A. Department of Pediatrics, University of Colorado, Anschutz Medical Campus, Aurora, CO 80045, U.S.A.
Gupta MB; Children's Health Research Institute, University of Western Ontario, London, Ontario N6C 2V5, Canada Department of Pediatrics and Biochemistry, University of Western Ontario, London, Ontario N6A 5C1, Canada.
Jansson T; Department of Obstetrics & Gynecology, University of Colorado, Anschutz Medical Campus, Aurora, CO 80045, U.S.A.

Clin Sci (Lond) ; 129(12): 1131-41, 2015 Dec.

Article em En | MEDLINE | ID: mdl-26374858

Assuntos

Sistema A de Transporte de Aminoácidos/metabolismo; Membrana Celular/metabolismo; Retardo do Crescimento Fetal/metabolismo; Trofoblastos/metabolismo; Adulto; Estudos de Casos e Controles; Células Cultivadas; Estresse do Retículo Endoplasmático; Complexos Endossomais de Distribuição Requeridos para Transporte/metabolismo; Feminino; Idade Gestacional; Humanos; Masculino; Alvo Mecanístico do Complexo 1 de Rapamicina; Alvo Mecanístico do Complexo 2 de Rapamicina; Complexos Multiproteicos/metabolismo; Ubiquitina-Proteína Ligases Nedd4; Gravidez; Complexo de Endopeptidases do Proteassoma; Transporte Proteico; Proteólise; Transdução de Sinais; Serina-Treonina Quinases TOR/metabolismo; Ubiquitina-Proteína Ligases/metabolismo; Ubiquitinação

Palavras-chave

maternalfetal exchange; mechanistic target of rapamycin (mTOR); pregnancy

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Trofoblastos / Membrana Celular / Sistema A de Transporte de Aminoácidos / Retardo do Crescimento Fetal Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male / Pregnancy Idioma: En Ano de publicação: 2015 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google