Helicobacter Pylori Infection: Diagnostic Strategies in Primary Diagnosis and After Therapy.
Dig Dis Sci
; 61(1): 19-24, 2016 Jan.
Article
em En
| MEDLINE
| ID: mdl-26391269
ABSTRACT
Accurate diagnosis of Helicobacter pylori infection pre- and post-treatment is mandatory in the current era of decreasing prevalence and increasing antibiotic resistance. The diagnostic performance of most tests is poorer in clinical situations with low bacterial density which is seen in conditions such as atrophic gastritis or intake of antisecretory and antibiotic medications. Noninvasive tests require less cost and resource but provide excellent accuracy; however, endoscopy with testing of gastric biopsy specimens is indicated where alarming symptoms are present or antibiotic susceptibility testing by culture is desired. Newer modalities such as polymerase chain reaction testing provide additional virulence and antibiotic sensitivity profiling. This article outlines new developments and the key parameters of each test, as careful selection of test modality within the clinical context is required for adequate management of infected symptomatic patients.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Testes Respiratórios
/
Testes Sorológicos
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Endoscopia Gastrointestinal
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Helicobacter pylori
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Infecções por Helicobacter
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Técnicas Bacteriológicas
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Humans
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article