Targeting Transcriptional Regulators of CD8+ T Cell Dysfunction to Boost Anti-Tumor Immunity.

Waugh, Katherine A; Leach, Sonia M; Slansky, Jill E

Waugh, Katherine A; Leach, Sonia M; Slansky, Jill E.

Afiliação

Waugh KA; University of Colorado School of Medicine, 12800 East 19th Avenue, Mail Stop 8333, Aurora, CO 80045, USA. Katherine.Waugh@UCDenver.edu.
Leach SM; Center for Genes, Environment and Health, National Jewish Health, Denver, CO 80206, USA. LeachS@NJHeath.org.
Slansky JE; University of Colorado School of Medicine, 12800 East 19th Avenue, Mail Stop 8333, Aurora, CO 80045, USA. Jill.Slansky@UCDenver.edu.

Vaccines (Basel) ; 3(3): 771-802, 2015 Sep 17.

Article em En | MEDLINE | ID: mdl-26393659

Palavras-chave

NF-κB; NFAT; PD-1; T cell dysfunction; T cell hypofunction; TIL; anergy; cancer immunotherapy; exhaustion; pathway analysis; tolerance; transcriptional regulation; transcriptome analysis; tumor-infiltrating T cells

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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2015 Tipo de documento: Article