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Autophosphorylation of CaMKK2 generates autonomous activity that is disrupted by a T85S mutation linked to anxiety and bipolar disorder.
Scott, John W; Park, Elizabeth; Rodriguiz, Ramona M; Oakhill, Jonathan S; Issa, Samah M A; O'Brien, Matthew T; Dite, Toby A; Langendorf, Christopher G; Wetsel, William C; Means, Anthony R; Kemp, Bruce E.
Afiliação
  • Scott JW; St Vincent's Institute and Department of Medicine, University of Melbourne, 41 Victoria Parade, Fitzroy, 3065, Australia.
  • Park E; Department of Psychiatry and Behavioral Sciences, Mouse Behavioral and Neuroendocrine Core Facility, Duke University Medical Center, Durham, NC 27710.
  • Rodriguiz RM; Department of Psychiatry and Behavioral Sciences, Mouse Behavioral and Neuroendocrine Core Facility, Duke University Medical Center, Durham, NC 27710.
  • Oakhill JS; St Vincent's Institute and Department of Medicine, University of Melbourne, 41 Victoria Parade, Fitzroy, 3065, Australia.
  • Issa SM; St Vincent's Institute and Department of Medicine, University of Melbourne, 41 Victoria Parade, Fitzroy, 3065, Australia.
  • O'Brien MT; St Vincent's Institute and Department of Medicine, University of Melbourne, 41 Victoria Parade, Fitzroy, 3065, Australia.
  • Dite TA; St Vincent's Institute and Department of Medicine, University of Melbourne, 41 Victoria Parade, Fitzroy, 3065, Australia.
  • Langendorf CG; St Vincent's Institute and Department of Medicine, University of Melbourne, 41 Victoria Parade, Fitzroy, 3065, Australia.
  • Wetsel WC; Department of Psychiatry and Behavioral Sciences, Mouse Behavioral and Neuroendocrine Core Facility, Duke University Medical Center, Durham, NC 27710.
  • Means AR; Departments of Cell Biology and Neurobiology, Duke University Medical Center, Durham, NC 27710.
  • Kemp BE; Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710.
Sci Rep ; 5: 14436, 2015 Sep 23.
Article em En | MEDLINE | ID: mdl-26395653
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ansiedade / Transtorno Bipolar / Quinase da Proteína Quinase Dependente de Cálcio-Calmodulina Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ansiedade / Transtorno Bipolar / Quinase da Proteína Quinase Dependente de Cálcio-Calmodulina Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article