Isocoumarins from the fermentation products of a plant entophytic fungus Penicillium oxalicum.
J Asian Nat Prod Res
; 17(9): 876-81, 2015.
Article
em En
| MEDLINE
| ID: mdl-26411648
ABSTRACT
Three new isocoumarins, terrecoumarins A-C (1-3), together with six known isocoumarins (4-9) were isolated from the fermentation products of the fungus Penicillium oxalicum 0403. Their structures were elucidated by spectroscopic methods, including extensive 1D and 2D NMR techniques. The anti-tobacco mosaic virus (anti-TMV) activities of 1-9 were evaluated. The results revealed that compound 1 showed high anti-TMV activity with inhibition rate 25.4 ± 3.5%. Other compounds also showed weak activity with inhibition rate in the range of 11.3-18.9%.
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1
Base de dados:
MEDLINE
Assunto principal:
Antivirais
/
Penicillium
/
Isocumarinas
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article