Quantitative-profiling of neurotransmitter abnormalities in the disease progression of experimental diabetic encephalopathy rat.

Zhou, Xueyan; Zhu, Qiuxiang; Han, Xiaowen; Chen, Renguo; Liu, Yaowu; Fan, Hongbin; Yin, Xiaoxing

Zhou, Xueyan; Zhu, Qiuxiang; Han, Xiaowen; Chen, Renguo; Liu, Yaowu; Fan, Hongbin; Yin, Xiaoxing.

Afiliação

Zhou X; a Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Jiangsu Center for the Collaboration and Innovation of Cancer Biotherapy, Xuzhou Medical College, 209 Tongshan Road, 221004 Xuzhou, China.
Zhu Q; a Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Jiangsu Center for the Collaboration and Innovation of Cancer Biotherapy, Xuzhou Medical College, 209 Tongshan Road, 221004 Xuzhou, China.
Han X; a Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Jiangsu Center for the Collaboration and Innovation of Cancer Biotherapy, Xuzhou Medical College, 209 Tongshan Road, 221004 Xuzhou, China.
Chen R; a Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Jiangsu Center for the Collaboration and Innovation of Cancer Biotherapy, Xuzhou Medical College, 209 Tongshan Road, 221004 Xuzhou, China.
Liu Y; a Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Jiangsu Center for the Collaboration and Innovation of Cancer Biotherapy, Xuzhou Medical College, 209 Tongshan Road, 221004 Xuzhou, China.
Fan H; b Department of Neurology, Affiliated Hospital of Xuzhou Medical College, Huaihai West Road 99, 221004 Xuzhou, China.
Yin X; a Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Jiangsu Center for the Collaboration and Innovation of Cancer Biotherapy, Xuzhou Medical College, 209 Tongshan Road, 221004 Xuzhou, China.

Can J Physiol Pharmacol ; 93(11): 1007-13, 2015 Nov.

Article em En | MEDLINE | ID: mdl-26426748

Assuntos

Encefalopatias/metabolismo; Encéfalo/metabolismo; Diabetes Mellitus Experimental/metabolismo; Progressão da Doença; Neurotransmissores/metabolismo; Animais; Encéfalo/patologia; Encefalopatias/patologia; Cromatografia Líquida/métodos; Diabetes Mellitus Experimental/patologia; Masculino; Espectrometria de Massas/métodos; Neurotransmissores/análise; Ratos; Ratos Sprague-Dawley

Palavras-chave

acetylcholine (ACh); acetylcholinesterase (AChE); acide Î³-aminobutirique (GABA); acétylcholine (ACh); acétylcholinestérase (AChE); cognitive dysfunction; diabetic encephalopathy (DE); dysfonction cognitive; encéphalopathie diabétique (ED); glutamate (Glu); glutamate decarboxylase (GAD); glutamate décarboxylase (GAD); neuro-inflammation; neuroinflammation; neurotransmetteur; neurotransmitter; Î³-aminobutyric acid (GABA)

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Encéfalo / Encefalopatias / Neurotransmissores / Progressão da Doença / Diabetes Mellitus Experimental Limite: Animals Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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