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Nitroreductase gene-directed enzyme prodrug therapy: insights and advances toward clinical utility.
Williams, Elsie M; Little, Rory F; Mowday, Alexandra M; Rich, Michelle H; Chan-Hyams, Jasmine V E; Copp, Janine N; Smaill, Jeff B; Patterson, Adam V; Ackerley, David F.
Afiliação
  • Williams EM; School of Biological Sciences, Victoria University of Wellington, Wellington 6140, New Zealand.
  • Little RF; School of Biological Sciences, Victoria University of Wellington, Wellington 6140, New Zealand.
  • Mowday AM; Auckland Cancer Society Research Centre, University of Auckland, Auckland 1023, New Zealand.
  • Rich MH; School of Biological Sciences, Victoria University of Wellington, Wellington 6140, New Zealand.
  • Chan-Hyams JV; School of Biological Sciences, Victoria University of Wellington, Wellington 6140, New Zealand.
  • Copp JN; Michael Smith Laboratories, University of British Columbia, Vancouver V6T 1Z4, BC, Canada.
  • Smaill JB; Auckland Cancer Society Research Centre, University of Auckland, Auckland 1023, New Zealand Maurice Wilkins Centre for Molecular Biodiscovery, School of Biological Sciences, University of Auckland, Auckland 1023, New Zealand.
  • Patterson AV; Auckland Cancer Society Research Centre, University of Auckland, Auckland 1023, New Zealand Maurice Wilkins Centre for Molecular Biodiscovery, School of Biological Sciences, University of Auckland, Auckland 1023, New Zealand.
  • Ackerley DF; School of Biological Sciences, Victoria University of Wellington, Wellington 6140, New Zealand Maurice Wilkins Centre for Molecular Biodiscovery, School of Biological Sciences, University of Auckland, Auckland 1023, New Zealand david.ackerley@vuw.ac.nz.
Biochem J ; 471(2): 131-53, 2015 Oct 15.
Article em En | MEDLINE | ID: mdl-26431849
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Aziridinas / Nitrorredutases / Pró-Fármacos / Terapia Genética / Proteínas de Escherichia coli / Neoplasias Experimentais Limite: Animals / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Aziridinas / Nitrorredutases / Pró-Fármacos / Terapia Genética / Proteínas de Escherichia coli / Neoplasias Experimentais Limite: Animals / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article