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Antitumor activity of a potent MEK inhibitor, TAK-733, against colorectal cancer cell lines and patient derived xenografts.
Lieu, Christopher H; Klauck, Peter J; Henthorn, Patrick K; Tentler, John J; Tan, Aik-Choon; Spreafico, Anna; Selby, Heather M; Britt, Blair C; Bagby, Stacey M; Arcaroli, John J; Messersmith, Wells A; Pitts, Todd M; Eckhardt, S Gail.
Afiliação
  • Lieu CH; Department of Medicine, Division of Medical Oncology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
  • Klauck PJ; Department of Medicine, Division of Medical Oncology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
  • Henthorn PK; Department of Medicine, Division of Medical Oncology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
  • Tentler JJ; Department of Medicine, Division of Medical Oncology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
  • Tan AC; Department of Medicine, Division of Medical Oncology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
  • Spreafico A; Department of Medicine, Division of Medical Oncology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
  • Selby HM; Department of Medicine, Division of Medical Oncology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
  • Britt BC; Department of Medicine, Division of Medical Oncology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
  • Bagby SM; Department of Medicine, Division of Medical Oncology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
  • Arcaroli JJ; Department of Medicine, Division of Medical Oncology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
  • Messersmith WA; Department of Medicine, Division of Medical Oncology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
  • Pitts TM; Department of Medicine, Division of Medical Oncology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
  • Eckhardt SG; Department of Medicine, Division of Medical Oncology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Oncotarget ; 6(33): 34561-72, 2015 Oct 27.
Article em En | MEDLINE | ID: mdl-26439693
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piridonas / Pirimidinonas / Neoplasias Colorretais / Resistencia a Medicamentos Antineoplásicos / MAP Quinase Quinase Quinases / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piridonas / Pirimidinonas / Neoplasias Colorretais / Resistencia a Medicamentos Antineoplásicos / MAP Quinase Quinase Quinases / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article