Kinases as druggable targets in trypanosomatid protozoan parasites.

Merritt, Christopher; Silva, Lisseth E; Tanner, Angela L; Stuart, Kenneth; Pollastri, Michael P

Merritt, Christopher; Silva, Lisseth E; Tanner, Angela L; Stuart, Kenneth; Pollastri, Michael P.

Afiliação

Merritt C; Seattle Biomedical Research Institute , 307 Westlake Avenue North, Suite 500, Seattle, Washington 98109-5219, United States.
Silva LE; Department of Chemistry & Chemical Biology, Northeastern University , 417 Egan Research Center, 360 Huntington Avenue, Boston, Massachusetts 02115, United States.
Tanner AL; Department of Chemistry & Chemical Biology, Northeastern University , 417 Egan Research Center, 360 Huntington Avenue, Boston, Massachusetts 02115, United States.
Stuart K; Seattle Biomedical Research Institute , 307 Westlake Avenue North, Suite 500, Seattle, Washington 98109-5219, United States.
Pollastri MP; Department of Chemistry & Chemical Biology, Northeastern University , 417 Egan Research Center, 360 Huntington Avenue, Boston, Massachusetts 02115, United States.

Chem Rev ; 114(22): 11280-304, 2014 Nov 26.

Article em En | MEDLINE | ID: mdl-26443079

Assuntos

Inibidores de Proteínas Quinases/farmacologia; Proteínas Quinases/metabolismo; Tripanossomicidas/farmacologia; Trypanosoma/efeitos dos fármacos; Animais; Inibidores de Proteínas Quinases/química; Tripanossomicidas/química; Trypanosoma/enzimologia

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Quinases / Tripanossomicidas / Trypanosoma / Inibidores de Proteínas Quinases Limite: Animals Idioma: En Ano de publicação: 2014 Tipo de documento: Article

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