Cobalt-Catalyzed Decarboxylative 2-Benzoylation of Oxazoles and Thiazoles with α-Oxocarboxylic Acids.
J Org Chem
; 80(21): 11065-72, 2015 Nov 06.
Article
em En
| MEDLINE
| ID: mdl-26449132
ABSTRACT
Cobalt-catalyzed decarboxylative cross-coupling of oxazoles and thiazoles with α-oxocarboxylic acids was developed through an sp(2) C-H bond functionalization process. This work represents the first example of cobalt-catalyzed decarboxylative C-H bond functionalization and provides an efficient means of building some important bioactive heteroaryl ketone derivatives.
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MEDLINE
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En
Ano de publicação:
2015
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Article