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Cobalt-Catalyzed Decarboxylative 2-Benzoylation of Oxazoles and Thiazoles with α-Oxocarboxylic Acids.
Yang, Ke; Chen, Xinyong; Wang, Yuqi; Li, Wanqing; Kadi, Adnan A; Fun, Hoong-Kun; Sun, Hao; Zhang, Yan; Li, Guigen; Lu, Hongjian.
Afiliação
  • Yang K; Institute of Chemistry & BioMedical Sciences, School of Chemistry and Chemical Engineering, Nanjing University , Nanjing 210093, China.
  • Chen X; Institute of Chemistry & BioMedical Sciences, School of Chemistry and Chemical Engineering, Nanjing University , Nanjing 210093, China.
  • Wang Y; Institute of Chemistry & BioMedical Sciences, School of Chemistry and Chemical Engineering, Nanjing University , Nanjing 210093, China.
  • Li W; Institute of Chemistry & BioMedical Sciences, School of Chemistry and Chemical Engineering, Nanjing University , Nanjing 210093, China.
  • Kadi AA; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University , Riyadh 11451, Saudi Arabia.
  • Fun HK; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University , Riyadh 11451, Saudi Arabia.
  • Sun H; Institute of Chemistry & BioMedical Sciences, School of Chemistry and Chemical Engineering, Nanjing University , Nanjing 210093, China.
  • Zhang Y; Institute of Chemistry & BioMedical Sciences, School of Chemistry and Chemical Engineering, Nanjing University , Nanjing 210093, China.
  • Li G; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University , Riyadh 11451, Saudi Arabia.
  • Lu H; Institute of Chemistry & BioMedical Sciences, School of Chemistry and Chemical Engineering, Nanjing University , Nanjing 210093, China.
J Org Chem ; 80(21): 11065-72, 2015 Nov 06.
Article em En | MEDLINE | ID: mdl-26449132
ABSTRACT
Cobalt-catalyzed decarboxylative cross-coupling of oxazoles and thiazoles with α-oxocarboxylic acids was developed through an sp(2) C-H bond functionalization process. This work represents the first example of cobalt-catalyzed decarboxylative C-H bond functionalization and provides an efficient means of building some important bioactive heteroaryl ketone derivatives.
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2015 Tipo de documento: Article
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2015 Tipo de documento: Article