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c-Met-mediated reactivation of PI3K/AKT signaling contributes to insensitivity of BRAF(V600E) mutant thyroid cancer to BRAF inhibition.
Byeon, Hyung Kwon; Na, Hwi Jung; Yang, Yeon Ju; Kwon, Hyeong Ju; Chang, Jae Won; Ban, Myung Jin; Kim, Won Shik; Shin, Dong Yeob; Lee, Eun Jig; Koh, Yoon Woo; Yoon, Joo-Heon; Choi, Eun Chang.
Afiliação
  • Byeon HK; Department of Otorhinolaryngology, Yonsei University College of Medicine, Seoul, Republic of Korea.
  • Na HJ; Department of Otorhinolaryngology, Yonsei University College of Medicine, Seoul, Republic of Korea.
  • Yang YJ; Department of Otorhinolaryngology, Yonsei University College of Medicine, Seoul, Republic of Korea.
  • Kwon HJ; Department of Pathology, Yonsei University College of Medicine, Seoul, Republic of Korea.
  • Chang JW; Department of Otorhinolaryngology, Chungnam National University College of Medicine, Daejeon, Republic of Korea.
  • Ban MJ; Department of Otorhinolaryngology, Soonchunhyang University College of Medicine, Cheonan, Republic of Korea.
  • Kim WS; Department of Otorhinolaryngology, Yonsei University College of Medicine, Seoul, Republic of Korea.
  • Shin DY; Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.
  • Lee EJ; Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.
  • Koh YW; Department of Otorhinolaryngology, Yonsei University College of Medicine, Seoul, Republic of Korea. ywkohent@yuhs.ac.
  • Yoon JH; Department of Otorhinolaryngology, Yonsei University College of Medicine, Seoul, Republic of Korea.
  • Choi EC; The Airway Mucus Institute, Yonsei University College of Medicine, Seoul, Republic of Korea.
Mol Carcinog ; 55(11): 1678-1687, 2016 Nov.
Article em En | MEDLINE | ID: mdl-26456083
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sulfonamidas / Sulfonas / Neoplasias da Glândula Tireoide / Regulação para Cima / Proteínas Proto-Oncogênicas c-met / Proteínas Proto-Oncogênicas B-raf / Indóis Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sulfonamidas / Sulfonas / Neoplasias da Glândula Tireoide / Regulação para Cima / Proteínas Proto-Oncogênicas c-met / Proteínas Proto-Oncogênicas B-raf / Indóis Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article