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Mitochondrial Phosphoenolpyruvate Carboxykinase Regulates Metabolic Adaptation and Enables Glucose-Independent Tumor Growth.
Vincent, Emma E; Sergushichev, Alexey; Griss, Takla; Gingras, Marie-Claude; Samborska, Bozena; Ntimbane, Thierry; Coelho, Paula P; Blagih, Julianna; Raissi, Thomas C; Choinière, Luc; Bridon, Gaëlle; Loginicheva, Ekaterina; Flynn, Breanna R; Thomas, Elaine C; Tavaré, Jeremy M; Avizonis, Daina; Pause, Arnim; Elder, Douglas J E; Artyomov, Maxim N; Jones, Russell G.
Afiliação
  • Vincent EE; Goodman Cancer Research Centre, McGill University, Montreal, QC H3A 1A3, Canada; Department of Physiology, McGill University, Montreal, QC H3G 1Y6, Canada.
  • Sergushichev A; ITMO University, Saint Petersburg 197101, Russia; Department of Pathology and Immunology, Washington University in St. Louis, St. Louis, MO 63110, USA.
  • Griss T; Goodman Cancer Research Centre, McGill University, Montreal, QC H3A 1A3, Canada; Department of Physiology, McGill University, Montreal, QC H3G 1Y6, Canada.
  • Gingras MC; Goodman Cancer Research Centre, McGill University, Montreal, QC H3A 1A3, Canada; Department of Biochemistry, McGill University, Montreal, QC H3G 1Y6, Canada.
  • Samborska B; Goodman Cancer Research Centre, McGill University, Montreal, QC H3A 1A3, Canada; Department of Physiology, McGill University, Montreal, QC H3G 1Y6, Canada.
  • Ntimbane T; Goodman Cancer Research Centre, McGill University, Montreal, QC H3A 1A3, Canada; Metabolomics Core Facility, Goodman Cancer Research Centre, McGill University, Montreal, QC H3A 1A3, Canada.
  • Coelho PP; Goodman Cancer Research Centre, McGill University, Montreal, QC H3A 1A3, Canada; Department of Physiology, McGill University, Montreal, QC H3G 1Y6, Canada.
  • Blagih J; Goodman Cancer Research Centre, McGill University, Montreal, QC H3A 1A3, Canada; Department of Physiology, McGill University, Montreal, QC H3G 1Y6, Canada.
  • Raissi TC; Goodman Cancer Research Centre, McGill University, Montreal, QC H3A 1A3, Canada; Department of Physiology, McGill University, Montreal, QC H3G 1Y6, Canada.
  • Choinière L; Goodman Cancer Research Centre, McGill University, Montreal, QC H3A 1A3, Canada; Metabolomics Core Facility, Goodman Cancer Research Centre, McGill University, Montreal, QC H3A 1A3, Canada.
  • Bridon G; Goodman Cancer Research Centre, McGill University, Montreal, QC H3A 1A3, Canada; Metabolomics Core Facility, Goodman Cancer Research Centre, McGill University, Montreal, QC H3A 1A3, Canada.
  • Loginicheva E; Department of Pathology and Immunology, Washington University in St. Louis, St. Louis, MO 63110, USA.
  • Flynn BR; Goodman Cancer Research Centre, McGill University, Montreal, QC H3A 1A3, Canada; Department of Physiology, McGill University, Montreal, QC H3G 1Y6, Canada.
  • Thomas EC; School of Biochemistry, Medical Sciences Building, University of Bristol, Bristol BS8 1TD, UK.
  • Tavaré JM; School of Biochemistry, Medical Sciences Building, University of Bristol, Bristol BS8 1TD, UK.
  • Avizonis D; Goodman Cancer Research Centre, McGill University, Montreal, QC H3A 1A3, Canada; Metabolomics Core Facility, Goodman Cancer Research Centre, McGill University, Montreal, QC H3A 1A3, Canada.
  • Pause A; Goodman Cancer Research Centre, McGill University, Montreal, QC H3A 1A3, Canada; Department of Biochemistry, McGill University, Montreal, QC H3G 1Y6, Canada.
  • Elder DJ; School of Biochemistry, Medical Sciences Building, University of Bristol, Bristol BS8 1TD, UK.
  • Artyomov MN; Department of Pathology and Immunology, Washington University in St. Louis, St. Louis, MO 63110, USA. Electronic address: martyomov@pathology.wustl.edu.
  • Jones RG; Goodman Cancer Research Centre, McGill University, Montreal, QC H3A 1A3, Canada; Department of Physiology, McGill University, Montreal, QC H3G 1Y6, Canada. Electronic address: russell.jones@mcgill.ca.
Mol Cell ; 60(2): 195-207, 2015 Oct 15.
Article em En | MEDLINE | ID: mdl-26474064
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Regulação Neoplásica da Expressão Gênica / Carcinoma Pulmonar de Células não Pequenas / Fosfoenolpiruvato Carboxiquinase (ATP) / Gluconeogênese / Neoplasias Pulmonares / Neoplasias Limite: Animals / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Regulação Neoplásica da Expressão Gênica / Carcinoma Pulmonar de Células não Pequenas / Fosfoenolpiruvato Carboxiquinase (ATP) / Gluconeogênese / Neoplasias Pulmonares / Neoplasias Limite: Animals / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article