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Mirabegron relaxes urethral smooth muscle by a dual mechanism involving ß3 -adrenoceptor activation and α1 -adrenoceptor blockade.
Alexandre, E C; Kiguti, L R; Calmasini, F B; Silva, F H; da Silva, K P; Ferreira, R; Ribeiro, C A; Mónica, F Z; Pupo, A S; Antunes, E.
Afiliação
  • Alexandre EC; Department of Pharmacology, University of Campinas (UNICAMP), Campinas, Brazil.
  • Kiguti LR; Department of Pharmacology, Institute of Biosciences, University of São Paulo State (UNESP), Botucatu, São Paulo, Brazil.
  • Calmasini FB; Department of Pharmacology, University of Campinas (UNICAMP), Campinas, Brazil.
  • Silva FH; Department of Pharmacology, University of Campinas (UNICAMP), Campinas, Brazil.
  • da Silva KP; Department of Pharmacology, Institute of Biosciences, University of São Paulo State (UNESP), Botucatu, São Paulo, Brazil.
  • Ferreira R; Hematology and Hemotherapy Center, Faculty of Medical Sciences, University of Campinas (UNICAMP), Campinas, Brazil.
  • Ribeiro CA; Department of Pharmacology, Institute of Biosciences, University of São Paulo State (UNESP), Botucatu, São Paulo, Brazil.
  • Mónica FZ; Department of Pharmacology, University of Campinas (UNICAMP), Campinas, Brazil.
  • Pupo AS; Department of Pharmacology, Institute of Biosciences, University of São Paulo State (UNESP), Botucatu, São Paulo, Brazil.
  • Antunes E; Department of Pharmacology, University of Campinas (UNICAMP), Campinas, Brazil.
Br J Pharmacol ; 173(3): 415-28, 2016 Feb.
Article em En | MEDLINE | ID: mdl-26493129
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tiazóis / Uretra / Agonistas de Receptores Adrenérgicos beta 3 / Antagonistas de Receptores Adrenérgicos alfa 1 / Acetanilidas Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tiazóis / Uretra / Agonistas de Receptores Adrenérgicos beta 3 / Antagonistas de Receptores Adrenérgicos alfa 1 / Acetanilidas Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2016 Tipo de documento: Article