Critical role of the Mac1/NOX2 pathway in mediating reactive microgliosis-generated chronic neuroinflammation and progressive neurodegeneration.

Chen, Shih-Heng; Oyarzabal, Esteban A; Hong, Jau-Shyong

Chen, Shih-Heng; Oyarzabal, Esteban A; Hong, Jau-Shyong.

Afiliação

Chen SH; Neurobiology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, USA. Electronic address: chens3@niehs.nih.gov.
Oyarzabal EA; Neurobiology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, USA; Neurobiology Curriculum, University of North Carolina Chapel Hill, Chapel Hill, NC, USA.
Hong JS; Neurobiology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, USA.

Curr Opin Pharmacol ; 26: 54-60, 2016 Feb.

Article em En | MEDLINE | ID: mdl-26498406

Assuntos

Antígeno de Macrófago 1/metabolismo; Glicoproteínas de Membrana/metabolismo; Microglia/metabolismo; NADPH Oxidases/metabolismo; Doenças Neurodegenerativas/metabolismo; Animais; Humanos; Inflamação/metabolismo; NADPH Oxidase 2; Transdução de Sinais; Receptores Toll-Like/metabolismo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Glicoproteínas de Membrana / Antígeno de Macrófago 1 / Microglia / NADPH Oxidases / Doenças Neurodegenerativas Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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