Three new sativene sesquiterpenoids from cultures of endophytic fungus Bipolaris eleusines.
J Asian Nat Prod Res
; 17(10): 982-7, 2015.
Article
em En
| MEDLINE
| ID: mdl-26499168
ABSTRACT
Three new sativene sesquiterpenoids, bipolenins A-C (1-3), together with two known analogs (4 and 5), were obtained from cultures of endophytic fungus Bipolaris eleusines. The structures of new compounds were elucidated on the basis of extensive spectroscopic analyses. Compound 2 showed weak inhibitory activities against lung cancer A-549 and breast cancer MCF-7 with IC50 values of 33.2 and 19.1 µmol, respectively.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Sesquiterpenos
/
Antineoplásicos
Limite:
Female
/
Humans
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article