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Discovery of α-mangostin as a novel competitive inhibitor against mutant isocitrate dehydrogenase-1.
Kim, Hyo-Joon; Fei, Xiang; Cho, Seok-Cheol; Choi, Bu Young; Ahn, Hee-Chul; Lee, Kyeong; Seo, Seung-Yong; Keum, Young-Sam.
Afiliação
  • Kim HJ; College of Pharmacy, Dongguk University, Goyang, Gyeonggi-do 410-820, Republic of Korea.
  • Fei X; College of Pharmacy and Gachon Institute of Pharmaceutical Sciences, Gachon University, Incheon 406-779, Republic of Korea.
  • Cho SC; Department of Pharmaceutical Science and Engineering, Seowon University, Cheongju, Chungbuk 361-742, Republic of Korea.
  • Choi BY; Department of Pharmaceutical Science and Engineering, Seowon University, Cheongju, Chungbuk 361-742, Republic of Korea.
  • Ahn HC; College of Pharmacy, Dongguk University, Goyang, Gyeonggi-do 410-820, Republic of Korea.
  • Lee K; College of Pharmacy, Dongguk University, Goyang, Gyeonggi-do 410-820, Republic of Korea.
  • Seo SY; College of Pharmacy and Gachon Institute of Pharmaceutical Sciences, Gachon University, Incheon 406-779, Republic of Korea.
  • Keum YS; College of Pharmacy, Dongguk University, Goyang, Gyeonggi-do 410-820, Republic of Korea. Electronic address: keum03@dongguk.edu.
Bioorg Med Chem Lett ; 25(23): 5625-31, 2015 Dec 01.
Article em En | MEDLINE | ID: mdl-26508549
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Xantonas / Descoberta de Drogas / Isocitrato Desidrogenase Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Xantonas / Descoberta de Drogas / Isocitrato Desidrogenase Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article