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Diagnosis of intrachromosomal amplification of chromosome 21 (iAMP21) by molecular cytogenetics in pediatric acute lymphoblastic leukemia.
Duployez, Nicolas; Boudry-Labis, Elise; Decool, Gauthier; Grzych, Guillaume; Grardel, Nathalie; Abou Chahla, Wadih; Preudhomme, Claude; Roche-Lestienne, Catherine.
Afiliação
  • Duployez N; Medical Cytogenetics Institute, Jeanne de Flandre Hospital Lille, France ; Laboratory of Hematology, Biology and Pathology Center Lille, France ; INSERM UMR-S 1172, Cancer Research Institute Lille, France.
  • Boudry-Labis E; Medical Cytogenetics Institute, Jeanne de Flandre Hospital Lille, France ; INSERM UMR-S 1172, Cancer Research Institute Lille, France.
  • Decool G; Laboratory of Hematology, Biology and Pathology Center Lille, France.
  • Grzych G; Laboratory of Hematology, Biology and Pathology Center Lille, France.
  • Grardel N; Laboratory of Hematology, Biology and Pathology Center Lille, France.
  • Abou Chahla W; Pediatric Hematology Department, Jeanne de Flandre Hospital Lille, France.
  • Preudhomme C; Laboratory of Hematology, Biology and Pathology Center Lille, France ; INSERM UMR-S 1172, Cancer Research Institute Lille, France.
  • Roche-Lestienne C; Medical Cytogenetics Institute, Jeanne de Flandre Hospital Lille, France ; INSERM UMR-S 1172, Cancer Research Institute Lille, France.
Clin Case Rep ; 3(10): 814-6, 2015 Oct.
Article em En | MEDLINE | ID: mdl-26509013
ABSTRACT
Intrachromosomal amplification of chromosome 21 (iAMP21) defines a distinct cytogenetic subgroup of B-cell precursor acute lymphoblastic leukemia (BCP-ALL) with poor prognosis that should be investigated in routine practice. Single-nucleotide polymorphism (SNP)-array provides a useful method to detect such cases showing a highly characteristic profile.
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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies / Prognostic_studies Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies / Prognostic_studies Idioma: En Ano de publicação: 2015 Tipo de documento: Article