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Identification of a novel 11ß-HSD1 inhibitor from a high-throughput screen of natural product extracts.
Park, Sung Bum; Park, Ji Seon; Jung, Won Hoon; Park, Areum; Jo, Sae Rom; Kim, Hee Youn; Dal Rhee, Sang; Ryu, Shi Yong; Jeong, Hye Gwang; Park, Seongsoon; Lee, Hyuk; Kim, Ki Young.
Afiliação
  • Park SB; Bio & Drug Discovery Division, Korea Research Institute of Chemical Technology, P.O. Box 107, Yuseong-gu, Daejeon 305-600, Republic of Korea; Department of Toxicology, College of Pharmacy, Chungnam National University, 99 Daehak-ro, Yuseong-gu, Daejeon 305-764, Republic of Korea.
  • Park JS; Department of Human and Environmental Toxicology, University of Science and Technology, 217 Gajeong-ro, Yuseong-gu, Daejeon 305-333, Republic of Korea.
  • Jung WH; Bio & Drug Discovery Division, Korea Research Institute of Chemical Technology, P.O. Box 107, Yuseong-gu, Daejeon 305-600, Republic of Korea.
  • Park A; Bio & Drug Discovery Division, Korea Research Institute of Chemical Technology, P.O. Box 107, Yuseong-gu, Daejeon 305-600, Republic of Korea; Department of Medicinal Chemistry and Pharmacology, University of Science and Technology, 217 Gajeong-ro, Yuseong-gu, Daejeon, 305-333, Republic of Korea.
  • Jo SR; Bio & Drug Discovery Division, Korea Research Institute of Chemical Technology, P.O. Box 107, Yuseong-gu, Daejeon 305-600, Republic of Korea; Department of Medicinal Chemistry and Pharmacology, University of Science and Technology, 217 Gajeong-ro, Yuseong-gu, Daejeon, 305-333, Republic of Korea.
  • Kim HY; Bio & Drug Discovery Division, Korea Research Institute of Chemical Technology, P.O. Box 107, Yuseong-gu, Daejeon 305-600, Republic of Korea.
  • Dal Rhee S; Bio & Drug Discovery Division, Korea Research Institute of Chemical Technology, P.O. Box 107, Yuseong-gu, Daejeon 305-600, Republic of Korea.
  • Ryu SY; Bio & Drug Discovery Division, Korea Research Institute of Chemical Technology, P.O. Box 107, Yuseong-gu, Daejeon 305-600, Republic of Korea.
  • Jeong HG; Department of Toxicology, College of Pharmacy, Chungnam National University, 99 Daehak-ro, Yuseong-gu, Daejeon 305-764, Republic of Korea.
  • Park S; Department of Chemistry, Center for NanoBio Applied Technology, Institute of Basic Sciences, Sungshin Women's University, 55 Dobon-ro 76ga-gil, Gangbuk-gu, Seoul 142-732, Republic of Korea.
  • Lee H; Bio & Drug Discovery Division, Korea Research Institute of Chemical Technology, P.O. Box 107, Yuseong-gu, Daejeon 305-600, Republic of Korea; Department of Medicinal Chemistry and Pharmacology, University of Science and Technology, 217 Gajeong-ro, Yuseong-gu, Daejeon, 305-333, Republic of Korea.
  • Kim KY; Bio & Drug Discovery Division, Korea Research Institute of Chemical Technology, P.O. Box 107, Yuseong-gu, Daejeon 305-600, Republic of Korea; Department of Medicinal Chemistry and Pharmacology, University of Science and Technology, 217 Gajeong-ro, Yuseong-gu, Daejeon, 305-333, Republic of Korea.
Pharmacol Res ; 102: 245-53, 2015 Dec.
Article em En | MEDLINE | ID: mdl-26515507
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Produtos Biológicos / 11-beta-Hidroxiesteroide Desidrogenase Tipo 1 Tipo de estudo: Diagnostic_studies Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Produtos Biológicos / 11-beta-Hidroxiesteroide Desidrogenase Tipo 1 Tipo de estudo: Diagnostic_studies Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2015 Tipo de documento: Article