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Detectable FLT3-ITD or RAS mutation at the time of transformation from MDS to AML predicts for very poor outcomes.
Badar, Talha; Patel, Keyur P; Thompson, Philip A; DiNardo, Courtney; Takahashi, Koichi; Cabrero, Monica; Borthakur, Gautam; Cortes, Jorge; Konopleva, Marina; Kadia, Tapan; Bohannan, Zach; Pierce, Sherry; Jabbour, Elias J; Ravandi, Farhad; Daver, Naval; Luthra, Raja; Kantarjian, Hagop; Garcia-Manero, Guillermo.
Afiliação
  • Badar T; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Patel KP; Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Thompson PA; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • DiNardo C; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Takahashi K; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Cabrero M; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Borthakur G; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Cortes J; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Konopleva M; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Kadia T; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Bohannan Z; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Pierce S; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Jabbour EJ; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Ravandi F; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Daver N; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Luthra R; Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Kantarjian H; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Garcia-Manero G; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address: ggarciam@mdanderson.org.
Leuk Res ; 39(12): 1367-74, 2015 Dec.
Article em En | MEDLINE | ID: mdl-26547258
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Síndromes Mielodisplásicas / Leucemia Mieloide Aguda / Genes ras / Tirosina Quinase 3 Semelhante a fms / Mutação Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Síndromes Mielodisplásicas / Leucemia Mieloide Aguda / Genes ras / Tirosina Quinase 3 Semelhante a fms / Mutação Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2015 Tipo de documento: Article