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Synthesis and biological profiling of 6- or 7-(het)aryl-7-deazapurine 4'-C-methylribonucleosides.
Naus, Petr; Caletková, Olga; Perlíková, Pavla; Postová Slavetínská, Lenka; Tloustová, Eva; Hodek, Jan; Weber, Jan; Dzubák, Petr; Hajdúch, Marián; Hocek, Michal.
Afiliação
  • Naus P; Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Gilead Sciences & IOCB Research Center, Flemingovo nam. 2, CZ-16610 Prague 6, Czech Republic.
  • Caletková O; Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Gilead Sciences & IOCB Research Center, Flemingovo nam. 2, CZ-16610 Prague 6, Czech Republic.
  • Perlíková P; Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Gilead Sciences & IOCB Research Center, Flemingovo nam. 2, CZ-16610 Prague 6, Czech Republic.
  • Postová Slavetínská L; Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Gilead Sciences & IOCB Research Center, Flemingovo nam. 2, CZ-16610 Prague 6, Czech Republic.
  • Tloustová E; Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Gilead Sciences & IOCB Research Center, Flemingovo nam. 2, CZ-16610 Prague 6, Czech Republic.
  • Hodek J; Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Gilead Sciences & IOCB Research Center, Flemingovo nam. 2, CZ-16610 Prague 6, Czech Republic.
  • Weber J; Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Gilead Sciences & IOCB Research Center, Flemingovo nam. 2, CZ-16610 Prague 6, Czech Republic.
  • Dzubák P; Institute of Molecular and Translational Medicine, Palacky University and University Hospital in Olomouc, Faculty of Medicine and Dentistry, Hnevotínská 5, 77515 Olomouc, Czech Republic.
  • Hajdúch M; Institute of Molecular and Translational Medicine, Palacky University and University Hospital in Olomouc, Faculty of Medicine and Dentistry, Hnevotínská 5, 77515 Olomouc, Czech Republic.
  • Hocek M; Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Gilead Sciences & IOCB Research Center, Flemingovo nam. 2, CZ-16610 Prague 6, Czech Republic; Department of Organic and Nuclear Chemistry, Faculty of Science, Charles University in Prague, Hlavova 8, CZ-1
Bioorg Med Chem ; 23(23): 7422-38, 2015 Dec 01.
Article em En | MEDLINE | ID: mdl-26558518

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antivirais / Nucleosídeos de Purina / Nucleotídeos de Purina / Pró-Fármacos / Antineoplásicos Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antivirais / Nucleosídeos de Purina / Nucleotídeos de Purina / Pró-Fármacos / Antineoplásicos Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article