Connexin 43 Is Necessary for Salivary Gland Branching Morphogenesis and FGF10-induced ERK1/2 Phosphorylation.

Yamada, Aya; Futagi, Masaharu; Fukumoto, Emiko; Saito, Kan; Yoshizaki, Keigo; Ishikawa, Masaki; Arakaki, Makiko; Hino, Ryoko; Sugawara, Yu; Ishikawa, Momoko; Naruse, Masahiro; Miyazaki, Kanako; Nakamura, Takashi; Fukumoto, Satoshi

Yamada, Aya; Futagi, Masaharu; Fukumoto, Emiko; Saito, Kan; Yoshizaki, Keigo; Ishikawa, Masaki; Arakaki, Makiko; Hino, Ryoko; Sugawara, Yu; Ishikawa, Momoko; Naruse, Masahiro; Miyazaki, Kanako; Nakamura, Takashi; Fukumoto, Satoshi.

Afiliação

Yamada A; From the Division of Pediatric Dentistry, Department of Oral Health and Development Sciences.
Futagi M; From the Division of Pediatric Dentistry, Department of Oral Health and Development Sciences.
Fukumoto E; From the Division of Pediatric Dentistry, Department of Oral Health and Development Sciences.
Saito K; From the Division of Pediatric Dentistry, Department of Oral Health and Development Sciences.
Yoshizaki K; Division of Orthodontics, Division of Oral Health, Growth and Development, Faculty of Dental Science, Kyushu University, Fukuoka 812-8582, Japan.
Ishikawa M; Operative Dentistry, Department of Restorative Dentistry Tohoku University Graduate School of Dentistry, Sendai 980-8575, Japan and.
Arakaki M; From the Division of Pediatric Dentistry, Department of Oral Health and Development Sciences.
Hino R; From the Division of Pediatric Dentistry, Department of Oral Health and Development Sciences.
Sugawara Y; From the Division of Pediatric Dentistry, Department of Oral Health and Development Sciences.
Ishikawa M; From the Division of Pediatric Dentistry, Department of Oral Health and Development Sciences.
Naruse M; From the Division of Pediatric Dentistry, Department of Oral Health and Development Sciences.
Miyazaki K; Division of Orthodontics, Division of Oral Health, Growth and Development, Faculty of Dental Science, Kyushu University, Fukuoka 812-8582, Japan.
Nakamura T; From the Division of Pediatric Dentistry, Department of Oral Health and Development Sciences.
Fukumoto S; From the Division of Pediatric Dentistry, Department of Oral Health and Development Sciences, fukumoto@dent.tohoku.ac.jp.

J Biol Chem ; 291(2): 904-12, 2016 Jan 08.

Article em En | MEDLINE | ID: mdl-26565022

Assuntos

Conexina 43/metabolismo; Fator 10 de Crescimento de Fibroblastos/farmacologia; Proteína Quinase 1 Ativada por Mitógeno/metabolismo; Proteína Quinase 3 Ativada por Mitógeno/metabolismo; Morfogênese/efeitos dos fármacos; Glândula Sublingual/embriologia; Glândula Sublingual/enzimologia; Animais; Becaplermina; Proteínas Morfogenéticas Ósseas/metabolismo; Linhagem Celular; Conexina 43/deficiência; Células Epiteliais/efeitos dos fármacos; Células Epiteliais/metabolismo; Fator 7 de Crescimento de Fibroblastos/farmacologia; Junções Comunicantes/efeitos dos fármacos; Junções Comunicantes/metabolismo; Ácido Glicirretínico/análogos & derivados; Ácido Glicirretínico/farmacologia; Camundongos Endogâmicos ICR; Camundongos Knockout; Ácidos Oleicos/farmacologia; Técnicas de Cultura de Órgãos; Peptídeos/farmacologia; Fenótipo; Fosforilação/efeitos dos fármacos; Fator de Crescimento Derivado de Plaquetas/farmacologia; Proteínas Proto-Oncogênicas c-sis/farmacologia; Receptor Tipo 1 de Fator de Crescimento de Fibroblastos/metabolismo; Receptor Tipo 2 de Fator de Crescimento de Fibroblastos/metabolismo; Glândula Sublingual/efeitos dos fármacos

Palavras-chave

branching morphogenesis; connexin; extracellular-signal-regulated kinase (ERK); fibroblast growth factor (FGF); gap junction; phosphorylation; salivary gland

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Glândula Sublingual / Conexina 43 / Proteína Quinase 1 Ativada por Mitógeno / Proteína Quinase 3 Ativada por Mitógeno / Fator 10 de Crescimento de Fibroblastos / Morfogênese Limite: Animals Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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