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Picomolar Inhibition of Plasmepsin V, an Essential Malaria Protease, Achieved Exploiting the Prime Region.
Gambini, Luca; Rizzi, Luca; Pedretti, Alessandro; Taglialatela-Scafati, Orazio; Carucci, Mario; Pancotti, Andrea; Galli, Corinna; Read, Martin; Giurisato, Emanuele; Romeo, Sergio; Russo, Ilaria.
Afiliação
  • Gambini L; Department of Pharmaceutical Sciences, Università degli Studi di Milano, Milan, Italy.
  • Rizzi L; Department of Pharmaceutical Sciences, Università degli Studi di Milano, Milan, Italy.
  • Pedretti A; Department of Pharmaceutical Sciences, Università degli Studi di Milano, Milan, Italy.
  • Taglialatela-Scafati O; Department of Chemistry of Natural Substances, Faculty of Pharmacy, Università di Napoli "Federico II", Naples, Italy.
  • Carucci M; Department of Experimental Medicine and Biochemical Sciences, Università degli Studi di Perugia, Perugia, Italy.
  • Pancotti A; Department of Pharmaceutical Sciences, Università degli Studi di Milano, Milan, Italy.
  • Galli C; Department of Pharmaceutical Sciences, Università degli Studi di Milano, Milan, Italy.
  • Read M; Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom.
  • Giurisato E; Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom.
  • Romeo S; Department of Pharmaceutical Sciences, Università degli Studi di Milano, Milan, Italy.
  • Russo I; Department of Experimental Medicine and Biochemical Sciences, Università degli Studi di Perugia, Perugia, Italy.
PLoS One ; 10(11): e0142509, 2015.
Article em En | MEDLINE | ID: mdl-26566224
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Plasmodium falciparum / Inibidores de Proteases / Proteínas de Protozoários / Ácido Aspártico Endopeptidases / Malária Falciparum / Antimaláricos Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Plasmodium falciparum / Inibidores de Proteases / Proteínas de Protozoários / Ácido Aspártico Endopeptidases / Malária Falciparum / Antimaláricos Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article