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Discovery of benzamides as potent human ß3 adrenergic receptor agonists.
Zhu, Cheng; Kar, Nam F; Li, Bing; Costa, Melissa; Dingley, Karen H; Di Salvo, Jerry; Ha, Sookhee N; Hurley, Amanda L; Li, Xiaofang; Miller, Randy R; Salituro, Gino M; Struthers, Mary; Weber, Ann E; Hale, Jeffrey J; Edmondson, Scott D.
Afiliação
  • Zhu C; Early Development and Discovery Sciences, Merck and Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ 07033, United States. Electronic address: cheng.zhu@merck.com.
  • Kar NF; Early Development and Discovery Sciences, Merck and Co., Inc., 126 East Lincoln Avenue, Rahway, NJ 07065, United States.
  • Li B; Early Development and Discovery Sciences, Merck and Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ 07033, United States.
  • Costa M; Early Development and Discovery Sciences, Merck and Co., Inc., 126 East Lincoln Avenue, Rahway, NJ 07065, United States.
  • Dingley KH; Early Development and Discovery Sciences, Merck and Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ 07033, United States.
  • Di Salvo J; Early Development and Discovery Sciences, Merck and Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ 07033, United States.
  • Ha SN; Early Development and Discovery Sciences, Merck and Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ 07033, United States.
  • Hurley AL; Early Development and Discovery Sciences, Merck and Co., Inc., 126 East Lincoln Avenue, Rahway, NJ 07065, United States.
  • Li X; Early Development and Discovery Sciences, Merck and Co., Inc., 126 East Lincoln Avenue, Rahway, NJ 07065, United States.
  • Miller RR; Early Development and Discovery Sciences, Merck and Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ 07033, United States.
  • Salituro GM; Early Development and Discovery Sciences, Merck and Co., Inc., 126 East Lincoln Avenue, Rahway, NJ 07065, United States.
  • Struthers M; Early Development and Discovery Sciences, Merck and Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ 07033, United States.
  • Weber AE; Early Development and Discovery Sciences, Merck and Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ 07033, United States.
  • Hale JJ; Early Development and Discovery Sciences, Merck and Co., Inc., 126 East Lincoln Avenue, Rahway, NJ 07065, United States.
  • Edmondson SD; Early Development and Discovery Sciences, Merck and Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ 07033, United States.
Bioorg Med Chem Lett ; 26(1): 55-9, 2016 Jan 01.
Article em En | MEDLINE | ID: mdl-26590100

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Benzamidas / Receptores Adrenérgicos beta 3 / Descoberta de Drogas / Agonistas de Receptores Adrenérgicos beta 3 Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Benzamidas / Receptores Adrenérgicos beta 3 / Descoberta de Drogas / Agonistas de Receptores Adrenérgicos beta 3 Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article