A versatile approach to flavones via a one-pot Pd(II)-catalyzed dehydrogenation/oxidative boron-Heck coupling sequence of chromanones.

Lee, Jun; Yu, Jihyun; Son, Seung Hwan; Heo, Jinyuk; Kim, Taelim; An, Ji-Young; Inn, Kyung-Soo; Kim, Nam-Jung

Lee, Jun; Yu, Jihyun; Son, Seung Hwan; Heo, Jinyuk; Kim, Taelim; An, Ji-Young; Inn, Kyung-Soo; Kim, Nam-Jung.

Afiliação

Lee J; College of Pharmacy, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemun-gu, Seoul, 130-701, Republic of Korea. kimnj@khu.ac.kr.

Org Biomol Chem ; 14(2): 777-784, 2016 Jan 14.

Article em En | MEDLINE | ID: mdl-26592753

ABSTRACT

ABSTRACT

A variety of flavones were expediently synthesized from readily accessible chromanones via a one-pot sequence involving Pd(II)-catalyzed dehydrogenation and oxidative boron-Heck coupling with arylboronic acid pinacol esters. In particular, the use of arylboronic acid pinacol esters was found to significantly improve the yield of the reaction.

Assuntos

Boro/química; Cromonas/química; Flavonas/síntese química; Compostos Organometálicos/química; Paládio/química; Catálise; Flavonas/química; Hidrogenação; Estrutura Molecular; Oxirredução

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Compostos Organometálicos / Paládio / Boro / Cromonas / Flavonas Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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