Mahogunin ring finger 1 confers cytoprotection against mutant SOD1 aggresomes and is defective in an ALS mouse model.

Chhangani, Deepak; Endo, Fumito; Amanullah, Ayeman; Upadhyay, Arun; Watanabe, Seiji; Mishra, Ribhav; Yamanaka, Koji; Mishra, Amit

Chhangani, Deepak; Endo, Fumito; Amanullah, Ayeman; Upadhyay, Arun; Watanabe, Seiji; Mishra, Ribhav; Yamanaka, Koji; Mishra, Amit.

Afiliação

Chhangani D; Cellular and Molecular Neurobiology Unit, Indian Institute of Technology Jodhpur, Rajasthan 342011, India.
Endo F; Department of Neuroscience and Pathobiology Research Institute of Environmental Medicine, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8601, Japan.
Amanullah A; Cellular and Molecular Neurobiology Unit, Indian Institute of Technology Jodhpur, Rajasthan 342011, India.
Upadhyay A; Cellular and Molecular Neurobiology Unit, Indian Institute of Technology Jodhpur, Rajasthan 342011, India.
Watanabe S; Department of Neuroscience and Pathobiology Research Institute of Environmental Medicine, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8601, Japan.
Mishra R; Cellular and Molecular Neurobiology Unit, Indian Institute of Technology Jodhpur, Rajasthan 342011, India.
Yamanaka K; Department of Neuroscience and Pathobiology Research Institute of Environmental Medicine, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8601, Japan. Electronic address: kojiyama@riem.nagoya-u.ac.jp.
Mishra A; Cellular and Molecular Neurobiology Unit, Indian Institute of Technology Jodhpur, Rajasthan 342011, India. Electronic address: amit@iitj.ac.in.

Neurobiol Dis ; 86: 16-28, 2016 Feb.

Article em En | MEDLINE | ID: mdl-26607786

Assuntos

Esclerose Lateral Amiotrófica/enzimologia; Esclerose Lateral Amiotrófica/patologia; Neurônios Motores/metabolismo; Neurônios Motores/patologia; Superóxido Dismutase/metabolismo; Ubiquitina-Proteína Ligases/metabolismo; Animais; Células COS; Sobrevivência Celular; Chlorocebus aethiops; Modelos Animais de Doenças; Células HEK293; Humanos; Camundongos; Camundongos Transgênicos; Medula Espinal/metabolismo; Medula Espinal/patologia; Superóxido Dismutase/genética; Superóxido Dismutase-1

Palavras-chave

Amyotrophic lateral sclerosis; Cytotoxicity; MGRN1; Protein aggregation; SOD1

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Superóxido Dismutase / Ubiquitina-Proteína Ligases / Esclerose Lateral Amiotrófica / Neurônios Motores Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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