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Synthesis of New Congeners of 1-methyl-3-aminoisoquinolines, Evaluation of Their Cytotoxic Activity, In Silico and In Vitro Study of Their Molecular Targets as PDE4B.
Lapa, Gennady B; Tsunoda, Toshiyuki; Shirasawa, Senji; Baryshnikova, Maria A; Evseev, Gregory G; Afanasyeva, Daria A; Chigorina, Elena A.
Afiliação
  • Lapa GB; Blokhin Cancer Center, Kashirskoe sh 24, Moscow, 115478, Russia.
  • Tsunoda T; Pirogov Russian National Research Medical University (RNRMU), Ostrovitianov str. 1, Moscow, 117997, Russia.
  • Shirasawa S; Department of Cell Biology, Faculty of Medicine, Fukuoka University, Fukuoka 814-0180, Japan.
  • Baryshnikova MA; Central Research Institute for Advanced Molecular Medicine, Fukuoka University, Fukuoka 814-0180, Japan.
  • Evseev GG; Department of Cell Biology, Faculty of Medicine, Fukuoka University, Fukuoka 814-0180, Japan.
  • Afanasyeva DA; Central Research Institute for Advanced Molecular Medicine, Fukuoka University, Fukuoka 814-0180, Japan.
  • Chigorina EA; Blokhin Cancer Center, Kashirskoe sh 24, Moscow, 115478, Russia.
Chem Biol Drug Des ; 87(4): 575-82, 2016 Apr.
Article em En | MEDLINE | ID: mdl-26613238
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores da Fosfodiesterase 4 / Isoquinolinas Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores da Fosfodiesterase 4 / Isoquinolinas Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article