Palladium-catalyzed C-H bond carboxylation of acetanilides: an efficient usage of N,N-dimethyloxamic acid as the carboxylate source.
Chem Commun (Camb)
; 52(6): 1286-9, 2016 Jan 21.
Article
em En
| MEDLINE
| ID: mdl-26616015
ABSTRACT
N,N-Dimethyloxamic acid can be successfully employed as a carboxylate precursor in the palladium-catalyzed direct C-H carboxylation of acetanilides. The reaction proceeds smoothly under mild conditions over a broad range of substrates with high functional group tolerance, affording substituted N-acyl anthranilic acids in moderate to high yields.
Texto completo:
1
Base de dados:
MEDLINE
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article