[DRUGS DESENSITIZATION]. / Induction de tolérance aux médicaments. D'excellents résultats quand le médicament est indispensable.

ABSTRACT

We now have the means to give a patient the drug he absolutely needs even if these have been responsible for immediate or delayed hypersensitivity reactions. We use so-called "desensitization protocols" which rely on strong experimental pathophysiological bases. We take as examples immediate hypersensitivity to aspirin/NSAID and chemotherapy and non-severe delayed hypersensitivity to antibiotic for which tolerance induction gives excellent results.