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Discovery and characterization of novel inhibitors of the sodium-coupled citrate transporter (NaCT or SLC13A5).
Huard, Kim; Brown, Janice; Jones, Jessica C; Cabral, Shawn; Futatsugi, Kentaro; Gorgoglione, Matthew; Lanba, Adhiraj; Vera, Nicholas B; Zhu, Yimin; Yan, Qingyun; Zhou, Yingjiang; Vernochet, Cecile; Riccardi, Keith; Wolford, Angela; Pirman, David; Niosi, Mark; Aspnes, Gary; Herr, Michael; Genung, Nathan E; Magee, Thomas V; Uccello, Daniel P; Loria, Paula; Di, Li; Gosset, James R; Hepworth, David; Rolph, Timothy; Pfefferkorn, Jeffrey A; Erion, Derek M.
Afiliação
  • Huard K; Worldwide Medicinal Chemistry, 610 Main street, Cambridge, MA 02139.
  • Brown J; Pharmacokinetics, Dynamics, and Metabolism, Eastern Point road, Groton, CT 06340.
  • Jones JC; Cardiovascular, Metabolic &Endocrine Disease Research Unit, 610 Main street, Cambridge, MA 02139.
  • Cabral S; Worldwide Medicinal Chemistry, Eastern Point road, Groton, CT 06340.
  • Futatsugi K; Worldwide Medicinal Chemistry, 610 Main street, Cambridge, MA 02139.
  • Gorgoglione M; Cardiovascular, Metabolic &Endocrine Disease Research Unit, 610 Main street, Cambridge, MA 02139.
  • Lanba A; Cardiovascular, Metabolic &Endocrine Disease Research Unit, 610 Main street, Cambridge, MA 02139.
  • Vera NB; Cardiovascular, Metabolic &Endocrine Disease Research Unit, 610 Main street, Cambridge, MA 02139.
  • Zhu Y; Cardiovascular, Metabolic &Endocrine Disease Research Unit, 610 Main street, Cambridge, MA 02139.
  • Yan Q; Cardiovascular, Metabolic &Endocrine Disease Research Unit, 610 Main street, Cambridge, MA 02139.
  • Zhou Y; Cardiovascular, Metabolic &Endocrine Disease Research Unit, 610 Main street, Cambridge, MA 02139.
  • Vernochet C; Cardiovascular, Metabolic &Endocrine Disease Research Unit, 610 Main street, Cambridge, MA 02139.
  • Riccardi K; Pharmacokinetics, Dynamics, and Metabolism, Eastern Point road, Groton, CT 06340.
  • Wolford A; Pharmacokinetics, Dynamics, and Metabolism, Eastern Point road, Groton, CT 06340.
  • Pirman D; Pharmacokinetics, Dynamics, and Metabolism, Eastern Point road, Groton, CT 06340.
  • Niosi M; Pharmacokinetics, Dynamics, and Metabolism, Eastern Point road, Groton, CT 06340.
  • Aspnes G; Worldwide Medicinal Chemistry, 610 Main street, Cambridge, MA 02139.
  • Herr M; Worldwide Medicinal Chemistry, Eastern Point road, Groton, CT 06340.
  • Genung NE; Worldwide Medicinal Chemistry, Eastern Point road, Groton, CT 06340.
  • Magee TV; Worldwide Medicinal Chemistry, 610 Main street, Cambridge, MA 02139.
  • Uccello DP; Worldwide Medicinal Chemistry, Eastern Point road, Groton, CT 06340.
  • Loria P; Pharmacokinetics, Dynamics, and Metabolism, Eastern Point road, Groton, CT 06340.
  • Di L; Pharmacokinetics, Dynamics, and Metabolism, Eastern Point road, Groton, CT 06340.
  • Gosset JR; Pharmacokinetics, Dynamics, and Metabolism, 610 Main street, Cambridge, MA 02139.
  • Hepworth D; Worldwide Medicinal Chemistry, 610 Main street, Cambridge, MA 02139.
  • Rolph T; Cardiovascular, Metabolic &Endocrine Disease Research Unit, 610 Main street, Cambridge, MA 02139.
  • Pfefferkorn JA; Cardiovascular, Metabolic &Endocrine Disease Research Unit, 610 Main street, Cambridge, MA 02139.
  • Erion DM; Cardiovascular, Metabolic &Endocrine Disease Research Unit, 610 Main street, Cambridge, MA 02139.
Sci Rep ; 5: 17391, 2015 Dec 01.
Article em En | MEDLINE | ID: mdl-26620127
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ácido Cítrico / Simportadores Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ácido Cítrico / Simportadores Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article