Macular Choroidal Thickness in Children: The Shandong Children Eye Study.
Invest Ophthalmol Vis Sci
; 56(13): 7646-52, 2015 Dec.
Article
em En
| MEDLINE
| ID: mdl-26624496
ABSTRACT
PURPOSE:
To examine the thickness of the macular choroid and its associations in school children aged 6 to 18 years.METHODS:
The school-based cross-sectional Shandong Children Eye Study included 6026 (94.7%) of 6364 eligible children fulfilling the inclusion criterion of an age from 4 to 18 years. Spectral-domain optical coherence tomography (SD-OCT) was performed for a subgroup of 972 school children aged 6+ years. All participants underwent ocular examinations, including measurement of visual acuity, cycloplegic refractometry, biometry, and SD-OCT (enhanced depth imaging mode) for measurement of choroidal thickness.RESULTS:
The study included 972 children (501 girls) with a mean age of 11.3 ± 3.3 years (range, 6-18 years) and mean axial length of 24.10 ± 1.56 mm (range, 16.57-28.82 mm). Mean choroidal thickness was thicker (P < 0.001) at 500 µm temporal to the foveola (290 ± 67 µm) than in the subfoveal region (283 ± 67 µm; range, 113-507 µm) and the region 500 µm superior to the fovea (283 ± 66 µm), where it was thicker (P < 0.001) than at 500 µm inferior of the foveola (281 ± 66 µm), and it was thinnest (P < 0.001) at 500 µm nasal of the foveola (268 ± 67 µm). In multivariate analysis, thicker SFCT was (overall correlation coefficient r 0.51) associated with shorter axial length (P < 0.001; standardized correlation coefficient ß -0.48; B -23.7; 95% confidence interval [CI] -27.2 to -20.3), male sex (P = 0.006; ß -0.08; B -10.7; 95% CI -18.3 to -3.11), and younger age (P = 0.04; ß -0.07; B -1.46; 95% CI -2.85 to -0.07).CONCLUSIONS:
As in adults, thicker SFCT in children and teenagers was markedly associated with shorter axial length, and to a lesser degree with male sex and older age. As in adults, increasing axial myopia in teenagers is associated with choroidal thinning and development of a leptochoroid.
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Base de dados:
MEDLINE
Assunto principal:
Acuidade Visual
/
Biometria
/
Corioide
/
Tomografia de Coerência Óptica
/
Comprimento Axial do Olho
Tipo de estudo:
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Limite:
Adolescent
/
Child
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Child, preschool
/
Female
/
Humans
/
Male
País como assunto:
Asia
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article