[Severe neutropenia as side effect of medical treatment in nontuberculous mycobacterial adenitis]. / Neutropenia grave secundaria al tratamiento médico de una adenitis por micobacterias no tuberculosas.
Rev Chilena Infectol
; 32(5): 584-7, 2015 Oct.
Article
em Es
| MEDLINE
| ID: mdl-26633119
ABSTRACT
Non-tuberculous mycobacterial adenitis is getting more common in our environment. Epidemiologic studies and clinical trials published nowadays are limited. We present a 2-years-old boy diagnosed of Mycobacterium intracellulare adenitis and severe neutropenia as side effect of combined treatment with oral azythromycin and rifabutin, which recovers after suspending the second one. Liver metabolism of macrolide seems to increase other drugs toxicity, in this case, rifabutin. The patient eventually needed surgery due to persistence of the adenitis despite treatment with antibiotics.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Rifabutina
/
Azitromicina
/
Antibacterianos
/
Neutropenia
Limite:
Child, preschool
/
Humans
/
Male
Idioma:
Es
Ano de publicação:
2015
Tipo de documento:
Article