Distinct Functions of Neutrophil in Cancer and Its Regulation.
Mediators Inflamm
; 2015: 701067, 2015.
Article
em En
| MEDLINE
| ID: mdl-26648665
ABSTRACT
Neutrophils are the most abundant of all white blood cells in the human circulation and are usually associated with inflammation and with fighting infections. In recent years the role immune cells play in cancer has been a matter of increasing interest. In this context the function of neutrophils is controversial as neutrophils were shown to possess both tumor promoting and tumor limiting properties. Here we provide an up-to-date review of the pro- and antitumor properties neutrophils possess as well as the environmental cues that regulate these distinct functions.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Neoplasias
/
Neutrófilos
Limite:
Animals
/
Humans
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article