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Integrative omics reveals MYCN as a global suppressor of cellular signalling and enables network-based therapeutic target discovery in neuroblastoma.
Duffy, David J; Krstic, Aleksandar; Halasz, Melinda; Schwarzl, Thomas; Fey, Dirk; Iljin, Kristiina; Mehta, Jai Prakash; Killick, Kate; Whilde, Jenny; Turriziani, Benedetta; Haapa-Paananen, Saija; Fey, Vidal; Fischer, Matthias; Westermann, Frank; Henrich, Kai-Oliver; Bannert, Steffen; Higgins, Desmond G; Kolch, Walter.
Afiliação
  • Duffy DJ; Systems Biology Ireland, University College Dublin, Belfield, Dublin, Ireland.
  • Krstic A; The Whitney Laboratory for Marine Bioscience, University of Florida, St. Augustine, Florida, USA.
  • Halasz M; Systems Biology Ireland, University College Dublin, Belfield, Dublin, Ireland.
  • Schwarzl T; Systems Biology Ireland, University College Dublin, Belfield, Dublin, Ireland.
  • Fey D; Systems Biology Ireland, University College Dublin, Belfield, Dublin, Ireland.
  • Iljin K; European Molecular Biology Laboratory (EMBL), Meyerhofstraße, Heidelberg, Germany.
  • Mehta JP; Systems Biology Ireland, University College Dublin, Belfield, Dublin, Ireland.
  • Killick K; VTT Technical Research Centre of Finland, Espoo, Finland.
  • Whilde J; Systems Biology Ireland, University College Dublin, Belfield, Dublin, Ireland.
  • Turriziani B; Systems Biology Ireland, University College Dublin, Belfield, Dublin, Ireland.
  • Haapa-Paananen S; Systems Biology Ireland, University College Dublin, Belfield, Dublin, Ireland.
  • Fey V; Systems Biology Ireland, University College Dublin, Belfield, Dublin, Ireland.
  • Fischer M; VTT Technical Research Centre of Finland, Espoo, Finland.
  • Westermann F; VTT Technical Research Centre of Finland, Espoo, Finland.
  • Henrich KO; Department of Paediatric Haematology and Oncology and Center for Molecular Medicine Cologne (CMMC), University Hospital Cologne, Cologne, Germany.
  • Bannert S; Division of NB Genomics, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Higgins DG; Division of NB Genomics, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Kolch W; Division of NB Genomics, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Oncotarget ; 6(41): 43182-201, 2015 Dec 22.
Article em En | MEDLINE | ID: mdl-26673823
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Nucleares / Genes myc / Proteínas Oncogênicas / Mapas de Interação de Proteínas / Neuroblastoma Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Nucleares / Genes myc / Proteínas Oncogênicas / Mapas de Interação de Proteínas / Neuroblastoma Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article