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Treatment with PF-04449913, an oral smoothened antagonist, in patients with myeloid malignancies: a phase 1 safety and pharmacokinetics study.
Martinelli, Giovanni; Oehler, Vivian G; Papayannidis, Cristina; Courtney, Rachel; Shaik, M Naveed; Zhang, Xiaoxi; O'Connell, Ashleigh; McLachlan, Karen R; Zheng, Xianxian; Radich, Jerald; Baccarani, Michele; Kantarjian, Hagop M; Levin, Wendy J; Cortes, Jorge E; Jamieson, Catriona.
Afiliação
  • Martinelli G; Department of Experimental, Diagnostic and Specialty Medicine (DIMES), University of Bologna, Bologna, Italy.
  • Oehler VG; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
  • Papayannidis C; Department of Experimental, Diagnostic and Specialty Medicine (DIMES), University of Bologna, Bologna, Italy.
  • Courtney R; Pfizer Oncology, La Jolla, CA, USA.
  • Shaik MN; Pfizer Oncology, La Jolla, CA, USA.
  • Zhang X; Pfizer Oncology, New York, NY, USA.
  • O'Connell A; Pfizer Oncology, Collegeville, PA, USA.
  • McLachlan KR; Pfizer Oncology, La Jolla, CA, USA.
  • Zheng X; Pfizer Oncology, La Jolla, CA, USA.
  • Radich J; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
  • Baccarani M; Department of Experimental, Diagnostic and Specialty Medicine (DIMES), University of Bologna, Bologna, Italy.
  • Kantarjian HM; Department of Leukemia, Division of Cancer Medicine, University of Texas, MD Anderson Cancer Center, Houston, TX, USA.
  • Levin WJ; Pfizer Oncology, La Jolla, CA, USA.
  • Cortes JE; Department of Leukemia, Division of Cancer Medicine, University of Texas, MD Anderson Cancer Center, Houston, TX, USA.
  • Jamieson C; Division of Regenerative Medicine and Moores Cancer Center, University of California San Diego, La Jolla, CA, USA. Electronic address: cjamieson@ucsd.edu.
Lancet Haematol ; 2(8): e339-46, 2015 Aug.
Article em En | MEDLINE | ID: mdl-26688487
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Compostos de Fenilureia / Benzimidazóis / Síndromes Mielodisplásicas / Leucemia Mieloide Aguda / Mielofibrose Primária Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Humans País como assunto: America do norte / Europa Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Compostos de Fenilureia / Benzimidazóis / Síndromes Mielodisplásicas / Leucemia Mieloide Aguda / Mielofibrose Primária Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Humans País como assunto: America do norte / Europa Idioma: En Ano de publicação: 2015 Tipo de documento: Article