Histone deacetylase activity and recurrent bacterial bronchitis in severe eosinophilic asthma.
Allergy
; 71(4): 571-5, 2016 Apr.
Article
em En
| MEDLINE
| ID: mdl-26715426
ABSTRACT
An increase in P13 Kinase activity and an associated reduction in histone deacetylase activity may contribute to both relative steroid insensitivity in patients with severe eosinophilic asthma and impaired macrophage scavenger function and susceptibility to recurrent infective bronchitis that may, in turn, contribute to further steroid insensitivity.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Asma
/
Infecções Bacterianas
/
Bronquite
Tipo de estudo:
Diagnostic_studies
Limite:
Adolescent
/
Adult
/
Aged
/
Child
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article