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O-alkylhydroxylamines as rationally-designed mechanism-based inhibitors of indoleamine 2,3-dioxygenase-1.
Malachowski, William P; Winters, Maria; DuHadaway, James B; Lewis-Ballester, Ariel; Badir, Shorouk; Wai, Jenny; Rahman, Maisha; Sheikh, Eesha; LaLonde, Judith M; Yeh, Syun-Ru; Prendergast, George C; Muller, Alexander J.
Afiliação
  • Malachowski WP; Department of Chemistry, Bryn Mawr College, 101 N. Merion Ave., Bryn Mawr, PA 19010-2899, USA. Electronic address: wmalacho@brynmawr.edu.
  • Winters M; Department of Chemistry, Bryn Mawr College, 101 N. Merion Ave., Bryn Mawr, PA 19010-2899, USA.
  • DuHadaway JB; Lankenau Institute for Medical Research, Wynnewood, PA 19096, USA.
  • Lewis-Ballester A; Department of Physiology and Biophysics, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA.
  • Badir S; Department of Chemistry, Bryn Mawr College, 101 N. Merion Ave., Bryn Mawr, PA 19010-2899, USA.
  • Wai J; Department of Chemistry, Bryn Mawr College, 101 N. Merion Ave., Bryn Mawr, PA 19010-2899, USA.
  • Rahman M; Department of Chemistry, Bryn Mawr College, 101 N. Merion Ave., Bryn Mawr, PA 19010-2899, USA.
  • Sheikh E; Department of Chemistry, Bryn Mawr College, 101 N. Merion Ave., Bryn Mawr, PA 19010-2899, USA.
  • LaLonde JM; Department of Chemistry, Bryn Mawr College, 101 N. Merion Ave., Bryn Mawr, PA 19010-2899, USA.
  • Yeh SR; Department of Physiology and Biophysics, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA.
  • Prendergast GC; Lankenau Institute for Medical Research, Wynnewood, PA 19096, USA; Department of Pathology, Anatomy & Cell Biology, Thomas Jefferson University, Philadelphia, PA 19104, USA; Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19104, USA.
  • Muller AJ; Lankenau Institute for Medical Research, Wynnewood, PA 19096, USA; Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19104, USA. Electronic address: mullera@mlhs.org.
Eur J Med Chem ; 108: 564-576, 2016 Jan 27.
Article em En | MEDLINE | ID: mdl-26717206
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Desenho de Fármacos / Indolamina-Pirrol 2,3,-Dioxigenase / Hidroxilaminas Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Desenho de Fármacos / Indolamina-Pirrol 2,3,-Dioxigenase / Hidroxilaminas Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article