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The Synthesis of the Metabolites of 2',3',5'-Tri-O-acetyl-N6-(3-hydroxyphenyl) Adenosine (WS070117).
Zhang, Wen-Xuan; Wu, Hong-Na; Li, Bo; Wu, Hong-Lin; Wang, Dong-Mei; Wu, Song.
Afiliação
  • Zhang WX; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100050, China. wxzhang@imm.ac.cn.
  • Wu HN; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100050, China. hongnawu@imm.ac.cn.
  • Li B; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100050, China. bolee@imm.ac.cn.
  • Wu HL; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100050, China. redwoods86@sina.com.
  • Wang DM; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100050, China. wangdmchina@imm.ac.cn.
  • Wu S; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100050, China. ws@imm.ac.cn.
Molecules ; 21(1): E8, 2015 Dec 28.
Article em En | MEDLINE | ID: mdl-26729072
ABSTRACT
Seven metabolites of 2',3',5'-tri-O-acetyl-N6-(3-hydroxyphenyl) adenosine (WS070117) were synthesized by deacetylation, hydrolysis, cyclization, sulfonylation and glycosylation reactions, respectively. All these compounds, which could be useful as material standards for metabolic research, were characterized by NMR and HPLC-MS (ESI) analyses.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Adenosina Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Adenosina Idioma: En Ano de publicação: 2015 Tipo de documento: Article