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Conformational changes of recombinant monoclonal antibodies by limited proteolytic digestion, stable isotope labeling, and liquid chromatography-mass spectrometry.
Ponniah, Gomathinayagam; Nowak, Christine; Kita, Adriana; Cheng, Guilong; Kori, Yekaterina; Liu, Hongcheng.
Afiliação
  • Ponniah G; Product Characterization, Alexion Pharmaceuticals, Cheshire, CT 06410, USA.
  • Nowak C; Product Characterization, Alexion Pharmaceuticals, Cheshire, CT 06410, USA.
  • Kita A; Product Characterization, Alexion Pharmaceuticals, Cheshire, CT 06410, USA.
  • Cheng G; Product Characterization, Alexion Pharmaceuticals, Cheshire, CT 06410, USA.
  • Kori Y; Product Characterization, Alexion Pharmaceuticals, Cheshire, CT 06410, USA.
  • Liu H; Product Characterization, Alexion Pharmaceuticals, Cheshire, CT 06410, USA. Electronic address: liuh@alxn.com.
Anal Biochem ; 497: 1-7, 2016 Mar 15.
Article em En | MEDLINE | ID: mdl-26747642
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Imunoglobulina G / Anticorpos Monoclonais Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Imunoglobulina G / Anticorpos Monoclonais Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article