A Borrelia burgdorferi Surface-Exposed Transmembrane Protein Lacking Detectable Immune Responses Supports Pathogen Persistence and Constitutes a Vaccine Target.

Kung, Faith; Kaur, Simarjot; Smith, Alexis A; Yang, Xiuli; Wilder, Cara N; Sharma, Kavita; Buyuktanir, Ozlem; Pal, Utpal

Kung, Faith; Kaur, Simarjot; Smith, Alexis A; Yang, Xiuli; Wilder, Cara N; Sharma, Kavita; Buyuktanir, Ozlem; Pal, Utpal.

Afiliação

Kung F; Department of Veterinary Medicine, University of Maryland-College Park and Virginia-Maryland Regional College of Veterinary Medicine, College Park.
Kaur S; Department of Veterinary Medicine, University of Maryland-College Park and Virginia-Maryland Regional College of Veterinary Medicine, College Park.
Smith AA; Department of Veterinary Medicine, University of Maryland-College Park and Virginia-Maryland Regional College of Veterinary Medicine, College Park.
Yang X; Department of Veterinary Medicine, University of Maryland-College Park and Virginia-Maryland Regional College of Veterinary Medicine, College Park.
Wilder CN; Department of Veterinary Medicine, University of Maryland-College Park and Virginia-Maryland Regional College of Veterinary Medicine, College Park.
Sharma K; Department of Veterinary Medicine, University of Maryland-College Park and Virginia-Maryland Regional College of Veterinary Medicine, College Park.
Buyuktanir O; Department of Microbiology, Faculty of Veterinary Medicine, Ondokuz Mayis University, Samsun, Turkey.
Pal U; Department of Veterinary Medicine, University of Maryland-College Park and Virginia-Maryland Regional College of Veterinary Medicine, College Park.

J Infect Dis ; 213(11): 1786-95, 2016 06 01.

Article em En | MEDLINE | ID: mdl-26747708

Assuntos

Proteínas da Membrana Bacteriana Externa/imunologia; Borrelia burgdorferi/imunologia; Vacinas contra Doença de Lyme/imunologia; Doença de Lyme/prevenção & controle; Animais; Anticorpos Antibacterianos/imunologia; Proteínas da Membrana Bacteriana Externa/biossíntese; Proteínas da Membrana Bacteriana Externa/genética; Borrelia burgdorferi/genética; Sistemas de Liberação de Medicamentos; Feminino; Imunidade Humoral; Imunogenicidade da Vacina; Doença de Lyme/imunologia; Doença de Lyme/microbiologia; Doença de Lyme/patologia; Camundongos Endogâmicos C3H; Mutagênese

Palavras-chave

BB0405; Borrelia burgdorferi; pathogen persistence; transmission-blocking; vaccine

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas da Membrana Bacteriana Externa / Doença de Lyme / Vacinas contra Doença de Lyme / Borrelia burgdorferi Limite: Animals Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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