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High-Throughput Assay and Discovery of Small Molecules that Interrupt Malaria Transmission.
Plouffe, David M; Wree, Melanie; Du, Alan Y; Meister, Stephan; Li, Fengwu; Patra, Kailash; Lubar, Aristea; Okitsu, Shinji L; Flannery, Erika L; Kato, Nobutaka; Tanaseichuk, Olga; Comer, Eamon; Zhou, Bin; Kuhen, Kelli; Zhou, Yingyao; Leroy, Didier; Schreiber, Stuart L; Scherer, Christina A; Vinetz, Joseph; Winzeler, Elizabeth A.
Afiliação
  • Plouffe DM; The Genomics Institute of the Novartis Research Foundation, 10675 John J. Hopkins Drive, San Diego, CA 92121, USA.
  • Wree M; Division of Pharmacology and Drug Discovery, Department of Pediatrics, University of California San Diego School of Medicine, 9500 Gilman Drive, La Jolla, CA 92093, USA.
  • Du AY; Division of Pharmacology and Drug Discovery, Department of Pediatrics, University of California San Diego School of Medicine, 9500 Gilman Drive, La Jolla, CA 92093, USA.
  • Meister S; Division of Pharmacology and Drug Discovery, Department of Pediatrics, University of California San Diego School of Medicine, 9500 Gilman Drive, La Jolla, CA 92093, USA.
  • Li F; Division of Infectious Disease, Department of Medicine, University of California San Diego School of Medicine, 9500 Gilman Drive, La Jolla, CA 92093, USA.
  • Patra K; Division of Infectious Disease, Department of Medicine, University of California San Diego School of Medicine, 9500 Gilman Drive, La Jolla, CA 92093, USA.
  • Lubar A; Division of Infectious Disease, Department of Medicine, University of California San Diego School of Medicine, 9500 Gilman Drive, La Jolla, CA 92093, USA.
  • Okitsu SL; Division of Pharmacology and Drug Discovery, Department of Pediatrics, University of California San Diego School of Medicine, 9500 Gilman Drive, La Jolla, CA 92093, USA.
  • Flannery EL; Division of Pharmacology and Drug Discovery, Department of Pediatrics, University of California San Diego School of Medicine, 9500 Gilman Drive, La Jolla, CA 92093, USA.
  • Kato N; Broad Institute, 415 Main Street, Cambridge MA 02142.
  • Tanaseichuk O; The Genomics Institute of the Novartis Research Foundation, 10675 John J. Hopkins Drive, San Diego, CA 92121, USA.
  • Comer E; Broad Institute, 415 Main Street, Cambridge MA 02142.
  • Zhou B; The Genomics Institute of the Novartis Research Foundation, 10675 John J. Hopkins Drive, San Diego, CA 92121, USA.
  • Kuhen K; The Genomics Institute of the Novartis Research Foundation, 10675 John J. Hopkins Drive, San Diego, CA 92121, USA.
  • Zhou Y; The Genomics Institute of the Novartis Research Foundation, 10675 John J. Hopkins Drive, San Diego, CA 92121, USA.
  • Leroy D; Medicines for Malaria Venture (MMV), PO Box 1826, 20 Route de Pré-Bois, 1215 Geneva 15, Switzerland.
  • Schreiber SL; Broad Institute, 415 Main Street, Cambridge MA 02142; Department of Chemistry and Chemical Biology, Harvard University, 7 Cambridge Center, Cambridge, MA 02142, USA.
  • Scherer CA; Broad Institute, 415 Main Street, Cambridge MA 02142.
  • Vinetz J; Division of Infectious Disease, Department of Medicine, University of California San Diego School of Medicine, 9500 Gilman Drive, La Jolla, CA 92093, USA.
  • Winzeler EA; Division of Pharmacology and Drug Discovery, Department of Pediatrics, University of California San Diego School of Medicine, 9500 Gilman Drive, La Jolla, CA 92093, USA. Electronic address: ewinzeler@ucsd.edu.
Cell Host Microbe ; 19(1): 114-26, 2016 Jan 13.
Article em En | MEDLINE | ID: mdl-26749441
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Plasmodium falciparum / Avaliação Pré-Clínica de Medicamentos / Ensaios de Triagem em Larga Escala / Malária / Antimaláricos Tipo de estudo: Evaluation_studies Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Plasmodium falciparum / Avaliação Pré-Clínica de Medicamentos / Ensaios de Triagem em Larga Escala / Malária / Antimaláricos Tipo de estudo: Evaluation_studies Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article