Discovery of Novel Haloalkane Dehalogenase Inhibitors.

Buryska, Tomas; Daniel, Lukas; Kunka, Antonin; Brezovsky, Jan; Damborsky, Jiri; Prokop, Zbynek

Buryska, Tomas; Daniel, Lukas; Kunka, Antonin; Brezovsky, Jan; Damborsky, Jiri; Prokop, Zbynek.

Afiliação

Buryska T; Loschmidt Laboratories, Department of Experimental Biology and Research Centre for Toxic Compounds in the Environment RECETOX, Faculty of Science, Masaryk University, Brno, Czech Republic.
Daniel L; International Clinical Research Center, St. Anne's University Hospital, Brno, Czech Republic.
Kunka A; Loschmidt Laboratories, Department of Experimental Biology and Research Centre for Toxic Compounds in the Environment RECETOX, Faculty of Science, Masaryk University, Brno, Czech Republic.
Brezovsky J; International Clinical Research Center, St. Anne's University Hospital, Brno, Czech Republic.
Damborsky J; Loschmidt Laboratories, Department of Experimental Biology and Research Centre for Toxic Compounds in the Environment RECETOX, Faculty of Science, Masaryk University, Brno, Czech Republic.
Prokop Z; Loschmidt Laboratories, Department of Experimental Biology and Research Centre for Toxic Compounds in the Environment RECETOX, Faculty of Science, Masaryk University, Brno, Czech Republic.

Appl Environ Microbiol ; 82(6): 1958-1965, 2016 Jan 15.

Article em En | MEDLINE | ID: mdl-26773086

Assuntos

Inibidores Enzimáticos/isolamento & purificação; Inibidores Enzimáticos/metabolismo; Hidrolases/antagonistas & inibidores; Hidrolases/química; Mycobacterium tuberculosis/enzimologia; Inibidores Enzimáticos/química; Modelos Moleculares; Simulação de Dinâmica Molecular; Estrutura Molecular; Conformação Proteica

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores Enzimáticos / Hidrolases / Mycobacterium tuberculosis Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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