The spectrum of onset of acute kidney injury in premature infants less than 30 weeks gestation.
J Perinatol
; 36(6): 474-80, 2016 06.
Article
em En
| MEDLINE
| ID: mdl-26796125
ABSTRACT
OBJECTIVE:
To determine risk factors for acute kidney injury (AKI) in preterm infants as a function of time of onset. STUDYDESIGN:
In this 5 1/2-year, single-center, retrospective study, incidence and timing of AKI was determined using modified Acute Kidney Injury Network criteria. Characteristics of newborns with and without AKI were compared by chi square and t-tests. Logistic regression was used to examine risk factors for AKI as a function of time of onset and potential confounders.RESULT:
AKI occurred in 30.3% of 357 neonates; 72.2% was stage 1. Gestational ages (GA), initial Cr, maternal magnesium and volume resuscitation were associated with early AKI (days 0 to 1). Volume resuscitation, umbilical arterial line and receipt of non-steroidal anti-inflammatory drug (NSAID) for patent ductus arteriosus were associated with intermediate AKI (days 2 to 5). GA, steroids for early hypotension, necrotizing enterocolitis and sepsis were associated with late AKI (⩾day 6).CONCLUSION:
Stage 1 AKI is a common morbidity in our population. Risk factors for AKI in our population differed with time of onset.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Sepse
/
Enterocolite Necrosante
/
Permeabilidade do Canal Arterial
/
Injúria Renal Aguda
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Prognostic_studies
Limite:
Female
/
Humans
/
Male
/
Newborn
País como assunto:
America do norte
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article