Statin Therapy and the Development of Cerebral Amyloid Angiopathy--A Rodent in Vivo Approach.

Reuter, Björn; Venus, Alexander; Grudzenski, Saskia; Heiler, Patrick; Schad, Lothar; Staufenbiel, Matthias; Hennerici, Michael G; Fatar, Marc

Reuter, Björn; Venus, Alexander; Grudzenski, Saskia; Heiler, Patrick; Schad, Lothar; Staufenbiel, Matthias; Hennerici, Michael G; Fatar, Marc.

Afiliação

Reuter B; Department of Neurology and Neurophysiology, University Freiburg, 79106 Freiburg, Germany. bjoern.reuter@uniklinik-freiburg.de.
Venus A; Department of Neurology, Universitätsmedizin Mannheim, Heidelberg University, 68167 Mannheim, Germany. venus.alexander@gmx.de.
Grudzenski S; Department of Neurology, Universitätsmedizin Mannheim, Heidelberg University, 68167 Mannheim, Germany. grudzenski@neuro.ma.uni-heidelberg.de.
Heiler P; Computer Assisted Clinical Medicine, Heidelberg University, 68167 Mannheim, Germany. patrick.heiler@siemens.com.
Schad L; Computer Assisted Clinical Medicine, Heidelberg University, 68167 Mannheim, Germany. lothar.schad@medma.uni-heidelberg.de.
Staufenbiel M; Nervous System Department, Novartis Institutes for Biomedical Research, 4002 Basel, Switzerland. staufenbiel.m@gmail.com.
Hennerici MG; Department of Neurology, Universitätsmedizin Mannheim, Heidelberg University, 68167 Mannheim, Germany. m.g.hennerici@eurostroke.eu.
Fatar M; Department of Neurology, Universitätsmedizin Mannheim, Heidelberg University, 68167 Mannheim, Germany. fatar@neuro.ma.uni-heidelberg.de.

Int J Mol Sci ; 17(1)2016 Jan 19.

Article em En | MEDLINE | ID: mdl-26797603

Assuntos

Anticolesterolemiantes/farmacologia; Atorvastatina/farmacologia; Angiopatia Amiloide Cerebral/tratamento farmacológico; Hemorragia Cerebral/tratamento farmacológico; Precursor de Proteína beta-Amiloide/genética; Precursor de Proteína beta-Amiloide/metabolismo; Animais; Angiopatia Amiloide Cerebral/genética; Angiopatia Amiloide Cerebral/metabolismo; Angiopatia Amiloide Cerebral/patologia; Hemorragia Cerebral/genética; Hemorragia Cerebral/metabolismo; Hemorragia Cerebral/patologia; Modelos Animais de Doenças; Expressão Gênica; Imageamento por Ressonância Magnética; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Transgênicos

Palavras-chave

APP23; CAA; amyloid; cerebral microbleeds; statins; transgenic mice

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hemorragia Cerebral / Angiopatia Amiloide Cerebral / Atorvastatina / Anticolesterolemiantes Limite: Animals Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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