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A first-in-human phase I study of the oral Notch inhibitor, LY900009, in patients with advanced cancer.
Pant, Shubham; Jones, Suzanne F; Kurkjian, Carla D; Infante, Jeffrey R; Moore, Kathleen N; Burris, Howard A; McMeekin, Donald S; Benhadji, Karim A; Patel, Bharvin K R; Frenzel, Martin J; Kursar, Jonathan D; Zamek-Gliszczynski, Maciej J; Yuen, Eunice S M; Chan, Edward M; Bendell, Johanna C.
Afiliação
  • Pant S; Stephenson Cancer Center University of Oklahoma, Oklahoma City, OK, USA; Sarah Cannon Research Institute, Nashville, TN, USA.
  • Jones SF; Sarah Cannon Research Institute, Nashville, TN, USA.
  • Kurkjian CD; Stephenson Cancer Center University of Oklahoma, Oklahoma City, OK, USA; Sarah Cannon Research Institute, Nashville, TN, USA.
  • Infante JR; Tennessee Oncology, Nashville, TN, USA; Sarah Cannon Research Institute, Nashville, TN, USA.
  • Moore KN; Stephenson Cancer Center University of Oklahoma, Oklahoma City, OK, USA; Sarah Cannon Research Institute, Nashville, TN, USA.
  • Burris HA; Tennessee Oncology, Nashville, TN, USA; Sarah Cannon Research Institute, Nashville, TN, USA.
  • McMeekin DS; Stephenson Cancer Center University of Oklahoma, Oklahoma City, OK, USA; Sarah Cannon Research Institute, Nashville, TN, USA.
  • Benhadji KA; Eli Lilly and Company, Indianapolis, IN, USA.
  • Patel BKR; Eli Lilly and Company, Indianapolis, IN, USA.
  • Frenzel MJ; Eli Lilly and Company, Indianapolis, IN, USA.
  • Kursar JD; Eli Lilly and Company, Indianapolis, IN, USA.
  • Zamek-Gliszczynski MJ; Eli Lilly and Company, Indianapolis, IN, USA.
  • Yuen ESM; Eli Lilly and Company, Windlesham, Surrey, UK.
  • Chan EM; Eli Lilly and Company, Indianapolis, IN, USA.
  • Bendell JC; Tennessee Oncology, Nashville, TN, USA; Sarah Cannon Research Institute, Nashville, TN, USA. Electronic address: jbendell@tnonc.com.
Eur J Cancer ; 56: 1-9, 2016 Mar.
Article em En | MEDLINE | ID: mdl-26798966
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores de Proteases / Dibenzazepinas / Alanina / Receptores Notch / Secretases da Proteína Precursora do Amiloide / Neoplasias / Antineoplásicos Tipo de estudo: Clinical_trials Limite: Adult / Aged / Female / Humans / Male / Middle aged País como assunto: America do norte Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores de Proteases / Dibenzazepinas / Alanina / Receptores Notch / Secretases da Proteína Precursora do Amiloide / Neoplasias / Antineoplásicos Tipo de estudo: Clinical_trials Limite: Adult / Aged / Female / Humans / Male / Middle aged País como assunto: America do norte Idioma: En Ano de publicação: 2016 Tipo de documento: Article