Effects of Low-Dose Escherichia coli Lipopolysaccharide-Induced Endotoxemia on Morphine Pharmacokinetics in an Animal Model.

Szkutnik-Fiedler, Danuta; Billert, Hanna; Grabowski, Tomasz; Lisiecka, Justyna; Michalak, Michal; Urjasz, Hanna; Grzeskowiak, Edmund

Szkutnik-Fiedler, Danuta; Billert, Hanna; Grabowski, Tomasz; Lisiecka, Justyna; Michalak, Michal; Urjasz, Hanna; Grzeskowiak, Edmund.

Afiliação

Szkutnik-Fiedler D; Departments of *Clinical Pharmacy and Biopharmacy, d.szkutnik@wp.pl.
Billert H; Experimental Anesthesiology.
Grabowski T; Department of Polpharma Biologics, Gdansk, Poland.
Lisiecka J; Departments of *Clinical Pharmacy and Biopharmacy.
Michalak M; Computer Sciences and Statistics, Poznan University of Medical Sciences, Poznan, Poland;
Urjasz H; Departments of *Clinical Pharmacy and Biopharmacy.
Grzeskowiak E; Departments of *Clinical Pharmacy and Biopharmacy.

Pain Med ; 17(8): 1407-15, 2016 08.

Article em En | MEDLINE | ID: mdl-26814265

Assuntos

Analgésicos Opioides/farmacologia; Endotoxemia/metabolismo; Morfina/farmacocinética; Animais; Modelos Animais de Doenças; Endotoxemia/induzido quimicamente; Escherichia coli; Feminino; Meia-Vida; Lipopolissacarídeos/toxicidade; Masculino; Coelhos

Palavras-chave

Low-Dose Endotoxemia; Morphine; Pharmacokinetics; Rabbits

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Endotoxemia / Analgésicos Opioides / Morfina Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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